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β(2)-Microglobulin is Required for the Full Expression of Xenobiotic-Induced Systemic Autoimmunity

Mercury exposure in both humans and mice is associated with features of systemic autoimmunity. Murine HgCl(2)-induced autoimmunity (mHgIA) requires MHC Class II, CD4(+) T-cells, co-stimulatory molecules, and interferon-γ (IFNγ), similar to spontaneous models of systemic lupus erythematosus (SLE). β(...

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Main Authors: Pollard, Kenneth. M., Hultman, Per, Toomey, Christopher B., Cauvi, David M., Kono, Dwight H.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257888/
https://ncbi.nlm.nih.gov/pubmed/21793797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/1547691X.2011.583614
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