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Monocytes from familial cold autoinflammatory syndrome patients are activated by mild hypothermia

BACKGROUND: Familial cold autoinflammatory syndrome (FCAS) is characterized by rash, fever, and arthralgia in response to cold exposure. CIAS1, the gene that codes for cryopyrin, is mutated in FCAS. Treatment with anakinra (IL-1 receptor antagonist) prevents symptoms, indicating a crucial role for I...

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書目詳細資料
發表在:J Allergy Clin Immunol
Main Authors: Rosengren, Sanna, Mueller, James L., Anderson, Justin P., Niehaus, Brian L., Misaghi, Amirhossein, Anderson, Scott, Boyle, David L., Hoffman, Hal M.
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322003/
https://ncbi.nlm.nih.gov/pubmed/17320940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2006.12.649
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