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Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist

BACKGROUND: Familial cold autoinflammatory syndrome (FCAS) is an autosomal dominant disorder characterised by recurrent episodes of rash, arthralgia, and fever after cold exposure. The genetic basis of this disease has been elucidated. Cryopyrin, the protein that is altered in FCAS, is one of the ad...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Lancet
Hauptverfasser: Hoffman, Hal M, Rosengren, Sanna, Boyle, David L, Cho, Jae Y, Nayar, Jyothi, Mueller, James L, Anderson, Justin P, Wanderer, Alan A, Firestein, Gary S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321997/
https://ncbi.nlm.nih.gov/pubmed/15541451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(04)17401-1
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