MicroRNA 223 3p Negatively Regulates the NLRP3 Inflammasome in Acute and Chronic Liver Injury

מאת Jimenez Calvente, Carolina, Del Pilar, Hana, Tameda, Masahiko, Johnson, Casey D., Feldstein, Ariel E.
הוצא לאור ב Mol Ther (2020)

Liver Bid-suppression for treatment of fibrosis associated with nonalcoholic steatohepatitis

מאת Eguchi, Akiko, Mollerat Du Jeu, Xavier De, Johnson, Casey D., Nektaria, Andronikou, Feldstein, Ariel E.
הוצא לאור ב J Hepatol (2015)

Circulating Extracellular Vesicles with Specific Proteome and Liver MicroRNAs Are Potential Biomarkers for Liver Injury in Experimental Fatty Liver Disease

מאת Povero, Davide, Eguchi, Akiko, Li, Hongying, Johnson, Casey D., Papouchado, Bettina G., Wree, Alexander, Messer, Karen, Feldstein, Ariel E.
הוצא לאור ב PLoS One (2014)

Differential regulation of inflammation and apoptosis in Fas-resistant hepatocyte-specific Bid-deficient mice

מאת Lazic, Milos, Eguchi, Akiko, Berk, Michael P., Povero, Davide, Papouchado, Bettina, Mulya, Anny, Johnson, Casey D., Feldstein, Ariel E.
הוצא לאור ב J Hepatol (2014)

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation and fibrosis

מאת Wree, Alexander, Eguchi, Akiko, McGeough, Matthew D., Pena, Carla A., Johnson, Casey D., Canbay, Ali, Hoffman, Hal M., Feldstein, Ariel E.
יצא לאור 2014

Redox nanoparticles as a novel treatment approach for inflammation and fibrosis associated with nonalcoholic steatohepatitis

מאת Eguchi, Akiko, Yoshitomi, Toru, Lazic, Milos, Johnson, Casey D, Vong, Long Binh, Wree, Alexander, Povero, Davide, Papouchado, Bettina G, Nagasaki, Yukio, Feldstein, Ariel E
הוצא לאור ב Nanomedicine (Lond) (2015)

Emricasan, a pan caspase inhibitor, improves survival and portal hypertension in a murine model of common bile-duct ligation

מאת Eguchi, Akiko, Koyama, Yukinori, Wree, Alexander, Johnson, Casey D., Nakamura, Ryota, Povero, Davide, Kneiber, David, Tameda, Masahiko, Contreras, Patricia, Spada, Al, Feldstein, Ariel E.
הוצא לאור ב J Mol Med (Berl) (2018)

Lipid-Induced Hepatocyte-Derived Extracellular Vesicles Regulate Hepatic Stellate Cells via MicroRNA Targeting Peroxisome Proliferator-Activated Receptor-γ

מאת Povero, Davide, Panera, Nadia, Eguchi, Akiko, Johnson, Casey D., Papouchado, Bettina G., de Araujo Horcel, Lucas, Pinatel, Eva M., Alisi, Anna, Nobili, Valerio, Feldstein, Ariel E.
הוצא לאור ב Cell Mol Gastroenterol Hepatol (2015)

TNF regulates transcription of NLRP3 inflammasome components and inflammatory molecules in cryopyrinopathies

מאת McGeough, Matthew D., Wree, Alexander, Inzaugarat, Maria E., Haimovich, Ariela, Johnson, Casey D., Peña, Carla A., Goldbach-Mansky, Raphaela, Broderick, Lori, Feldstein, Ariel E., Hoffman, Hal M.
הוצא לאור ב J Clin Invest (2017)

NLRP3 inflammasome activation in hepatic stellate cells induces murine liver fibrosis

מאת Inzaugarat, Maria Eugenia, Johnson, Casey D., Holtmann, Theresa Maria, McGeough, Matthew D., Trautwein, Christian, Papouchado, Bettina G., Schwabe, Robert, Hoffman, Hal M., Wree, Alexander, Feldstein, Ariel E.
הוצא לאור ב Hepatology (2019)

Neutrophils contribute to spontaneous resolution of liver inflammation and fibrosis via microRNA-223

מאת Calvente, Carolina Jimenez, Tameda, Masahiko, Johnson, Casey D., del Pilar, Hana, Lin, Yun Chin, Adronikou, Nektaria, De Mollerat Du Jeu, Xavier, Llorente, Cristina, Boyer, Josh, Feldstein, Ariel E.
הוצא לאור ב J Clin Invest (2019)

Oxidized Derivatives of Linoleic Acid in Pediatric Metabolic Syndrome: Is Their Pathogenic Role Modulated by the Genetic Background and the Gut Microbiota?

מאת Tricò, Domenico, Di Sessa, Anna, Caprio, Sonia, Chalasani, Naga, Liu, Wanqing, Liang, Tiebing, Graf, Joerg, Herzog, Raimund I., Johnson, Casey D., Umano, Giuseppina Rosaria, Feldstein, Ariel E., Santoro, Nicola
הוצא לאור ב Antioxid Redox Signal (2019)

Oxidized linoleic acid metabolites induce liver mitochondrial dysfunction, apoptosis, and NLRP3 activation in mice

מאת Schuster, Susanne, Johnson, Casey D., Hennebelle, Marie, Holtmann, Theresa, Taha, Ameer Y., Kirpich, Irina A., Eguchi, Akiko, Ramsden, Christopher E., Papouchado, Bettina G., McClain, Craig J., Feldstein, Ariel E.
הוצא לאור ב J Lipid Res (2018)

NLRP3 inflammasome driven liver injury and fibrosis: roles of IL- 17 and TNF

מאת Wree, Alexander, McGeough, Matthew D., Inzaugarat, Maria Eugenia, Eguchi, Akiko, Schuster, Susanne, Johnson, Casey D., Peña, Carla A., Geisler, Lukas J., Papouchado, Bettina G, Hoffman, Hal M., Feldstein, Ariel E.
הוצא לאור ב Hepatology (2017)

Differential activation of hepatic iNKT cell subsets plays a key role in progression of nonalcoholic steatohepatitis

מאת Maricic, Igor, Marrero, Idania, Eguchi, Akiko, Nakamura, Ryota, Johnson, Casey D., Dasgupta, Suryasarathi, Hernandez, Carolyn D., Nguyen, Phirum Sam, Swafford, Austin D., Knight, Rob, Feldstein, Ariel E., Loomba, Rohit, Kumar, Vipin
הוצא לאור ב J Immunol (2018)

ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model

מאת Schuster-Gaul, Susanne, Geisler, Lukas Jonathan, McGeough, Matthew D., Johnson, Casey D., Zagorska, Anna, Li, Li, Wree, Alexander, Barry, Vivian, Mikaelian, Igor, Jih, Lily J., Papouchado, Bettina G., Budas, Grant, Hoffman, Hal M., Feldstein, Ariel E.
הוצא לאור ב JCI Insight (2020)

Effects of diets enriched in linoleic acid and its peroxidation products on brain fatty acids, oxylipins, and aldehydes in mice

מאת Ramsden, Christopher E., Hennebelle, Marie, Schuster, Susanne, Keyes, Gregory S., Johnson, Casey D., Kirpich, Irina A., Dahlen, Jeff E., Horowitz, Mark S., Zamora, Daisy, Feldstein, Ariel E., McClain, Craig J., Muhlhausler, Beverly S., Makrides, Maria, Gibson, Robert A., Taha, Ameer Y.
הוצא לאור ב Biochim Biophys Acta Mol Cell Biol Lipids (2018)

Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis

מאת Gaul, Susanne, Leszczynska, Aleksandra, Alegre, Fernando, Kaufmann, Benedikt, Johnson, Casey D., Adams, Leon A., Wree, Alexander, Damm, Georg, Seehofer, Daniel, Calvente, Carolina J., Povero, Davide, Kisseleva, Tatiana, Eguchi, Akiko, McGeough, Matthew D., Hoffman, Hal M., Pelegrin, Pablo, Laufs, Ulrich, Feldstein, Ariel E.
הוצא לאור ב J Hepatol (2020)

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

מאת Mridha, Auvro R., Wree, Alexander, Robertson, Avril A.B., Yeh, Matthew M., Johnson, Casey D., Van Rooyen, Derrick M., Haczeyni, Fahrettin, Teoh, Narci C.-H., Savard, Christopher, Ioannou, George N., Masters, Seth L., Schroder, Kate, Cooper, Matthew A., Feldstein, Ariel E., Farrell, Geoffrey C.
הוצא לאור ב J Hepatol (2017)