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Redox nanoparticles as a novel treatment approach for inflammation and fibrosis associated with nonalcoholic steatohepatitis

AIM: Oxidative stress (OS) is largely thought to be a central mechanism responsible for liver damage, inflammation and fibrosis in nonalcoholic steatohepatitis (NASH). Our aim was to investigate whether suppression of OS in the liver via redox nanoparticles (RNPs) reduces liver damage in a mouse mod...

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Detalhes bibliográficos
Publicado no:Nanomedicine (Lond)
Main Authors: Eguchi, Akiko, Yoshitomi, Toru, Lazic, Milos, Johnson, Casey D, Vong, Long Binh, Wree, Alexander, Povero, Davide, Papouchado, Bettina G, Nagasaki, Yukio, Feldstein, Ariel E
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910954/
https://ncbi.nlm.nih.gov/pubmed/26020857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.15.87
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