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Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis
BACKGROUND &AIMS: Increased hepatocyte death contributes to the pathology of acute and chronic liver diseases. The role of hepatocyte pyroptosis and extracellular inflammasome release in liver disease is unknown. METHODS: We used primary mouse and human hepatocytes, hepatocyte-specific L351P Nlr...
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| Yayımlandı: | J Hepatol |
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7749849/ https://ncbi.nlm.nih.gov/pubmed/32763266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2020.07.041 |
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