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NLRP3 inflammasome activation in hepatic stellate cells induces murine liver fibrosis

The NLRP3 inflammasome plays an important role in liver fibrosis development. However, the mechanisms involved in NLRP3-induced fibrosis are unclear. Our aim was to test the hypothesis that the NLRP3 inflammasome in hepatic stellate cells (HSC) can directly regulate their activation and contribute t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Hepatology
Päätekijät: Inzaugarat, Maria Eugenia, Johnson, Casey D., Holtmann, Theresa Maria, McGeough, Matthew D., Trautwein, Christian, Papouchado, Bettina G., Schwabe, Robert, Hoffman, Hal M., Wree, Alexander, Feldstein, Ariel E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351190/
https://ncbi.nlm.nih.gov/pubmed/30180270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30252
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