NLRP3 inflammasome activation in hepatic stellate cells induces murine liver fibrosis

The NLRP3 inflammasome plays an important role in liver fibrosis development. However, the mechanisms involved in NLRP3-induced fibrosis are unclear. Our aim was to test the hypothesis that the NLRP3 inflammasome in hepatic stellate cells (HSC) can directly regulate their activation and contribute t...

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Bibliographische Detailangaben
Veröffentlicht in:Hepatology
Hauptverfasser: Inzaugarat, Maria Eugenia, Johnson, Casey D., Holtmann, Theresa Maria, McGeough, Matthew D., Trautwein, Christian, Papouchado, Bettina G., Schwabe, Robert, Hoffman, Hal M., Wree, Alexander, Feldstein, Ariel E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351190/
https://ncbi.nlm.nih.gov/pubmed/30180270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30252
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