NLRP3 inflammasome activation is required for fibrosis development in NAFLD

NLR inflammasomes, caspase 1 activation platforms critical for processing key pro-inflammatory cytokines, have been implicated in the development of nonalcoholic fatty liver disease (NAFLD). As the direct role of the NLRP3 inflammasome remains unclear, we tested effects of persistent NLRP3 activatio...

Full description

Saved in:
Bibliographic Details
Published in:J Mol Med (Berl)
Main Authors: Wree, Alexander, McGeough, Matthew D., Peña, Carla A., Schlattjan, Martin, Li, Hongying, Inzaugarat, Maria Eugenia, Messer, Karen, Canbay, Ali, Hoffman, Hal M., Feldstein, Ariel E.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349416/
https://ncbi.nlm.nih.gov/pubmed/24861026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-014-1170-1
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items