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Interleukin-6 is a Marker of Inflammation with No Direct Role in Inflammasome-Mediated Mouse Models()

IL-6 is a known downstream target of IL-1β, consistently increased in serum from patients with NLRP3 inflammasome-mediated conditions. Therefore, IL-6 could be a therapeutic target in the treatment of IL-1β-provoked inflammation. IL-6 was increased in serum with accompanying neutrophilia in tissues...

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Detalhes bibliográficos
Main Authors: McGeough, Matthew D., Pena, Carla A., Mueller, James L., Pociask, Derek A., Broderick, Lori, Hoffman, Hal M., Brydges, Susannah D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495128/
https://ncbi.nlm.nih.gov/pubmed/22904305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101737
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