Constitutively Activated NLRP3 Inflammasome Causes Inflammation and Abnormal Skeletal Development in Mice

The NLRP3 inflammasome complex is responsible for maturation of the pro-inflammatory cytokine, IL-1β. Mutations in NLRP3 are responsible for the cryopyrinopathies, a spectrum of conditions including neonatal-onset multisystem inflammatory disease (NOMID). While excessive production of IL-1β and syst...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bonar, Sheri L., Brydges, Susannah D., Mueller, James L., McGeough, Matthew D., Pena, Carla, Chen, Debbie, Grimston, Susan K., Hickman-Brecks, Cynthia L., Ravindran, Soumya, McAlinden, Audrey, Novack, Deborah V., Kastner, Daniel L., Civitelli, Roberto, Hoffman, Hal M., Mbalaviele, Gabriel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338787/
https://ncbi.nlm.nih.gov/pubmed/22558291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035979
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados