Genetic Modification of Adeno-Associated Viral Vector Type 2 Capsid Enhances Gene Transfer Efficiency in Polarized Human Airway Epithelial Cells

Por White, April F., Mazur, Marina, Sorscher, Eric J., Zinn, Kurt R., Ponnazhagan, Selvarangan
Publicado no Hum Gene Ther (2008)

Activation of the Unfolded Protein Response by ΔF508 CFTR

Por Bartoszewski, Rafal, Rab, Andras, Jurkuvenaite, Asta, Mazur, Marina, Wakefield, John, Collawn, James F., Bebők, Zsuzsa
Publicado em 2008

BIOELECTRIC EFFECTS OF QUININE ON POLARIZED AIRWAY EPITHELIAL CELLS

Por Rowe, Steven M., Bates, Eleanor, Miller, Stacey, Alexander, Mariah, Mazur, Marina, Fortenberry, James A., Bebok, Zsuzsa, Sorscher, Eric J.
Publicado em 2007

Activation of the Cystic Fibrosis Transmembrane Conductance Regulator by the Flavonoid Quercetin: Potential Use as a Biomarker of ΔF508 Cystic Fibrosis Transmembrane Conductance Re...

Por Pyle, Louise C., Fulton, Jennifer C., Sloane, Peter A., Backer, Kyle, Mazur, Marina, Prasain, Jeevan, Barnes, Stephen, Clancy, J. P., Rowe, Steven M.
Publicado em 2010

Vaporized E-Cigarette Liquids Induce Ion Transport Dysfunction in Airway Epithelia

Por Lin, Vivian Y., Fain, Matthew D., Jackson, Patricia L., Berryhill, Taylor F., Wilson, Landon S., Mazur, Marina, Barnes, Stephen J., Blalock, J. Edwin, Raju, S. Vamsee, Rowe, Steven M.
Publicado no Am J Respir Cell Mol Biol (2019)

Suppression of CFTR premature termination codons and rescue of CFTR protein and function by the synthetic aminoglycoside NB54

Por Rowe, Steven M., Sloane, Peter, Tang, Li Ping, Backer, Kyle, Mazur, Marina, Buckley-Lanier, Jessica, Nudelman, Igor, Belakhov, Valery, Bebok, Zsuzsa, Schwiebert, Erik, Baasov, Timor, Bedwell, David M.
Publicado em 2011

MicroRNA-145 Antagonism Reverses TGF-β Inhibition of F508del CFTR Correction in Airway Epithelia

Por Lutful Kabir, Farruk, Ambalavanan, Namasivayam, Liu, Gang, Li, Peng, Solomon, George M., Lal, Charitharth V., Mazur, Marina, Halloran, Brian, Szul, Tomasz, Gerthoffer, William T., Rowe, Steven M., Harris, William T.
Publicado no Am J Respir Crit Care Med (2018)

Analysis of cystic fibrosis–associated P67L CFTR illustrates barriers to personalized therapeutics for orphan diseases

Por Sabusap, Carleen M., Wang, Wei, McNicholas, Carmel M., Chung, W. Joon, Fu, Lianwu, Wen, Hui, Mazur, Marina, Kirk, Kevin L., Collawn, James F., Hong, Jeong S., Sorscher, Eric J.
Publicado no JCI Insight (2016)

Excess mucus viscosity and airway dehydration impact COPD airway clearance

Por Lin, Vivian Y., Kaza, Niroop, Birket, Susan E., Kim, Harrison, Edwards, Lloyd J., LaFontaine, Jennifer, Liu, Linbo, Mazur, Marina, Byzek, Stephen A., Hanes, Justin, Tearney, Guillermo J., Raju, S. Vamsee, Rowe, Steven M.
Publicado no Eur Respir J (2020)

An Adeno-Associated Viral Vector Capable of Penetrating the Mucus Barrier to Inhaled Gene Therapy

Por Duncan, Gregg A., Kim, Namho, Colon-Cortes, Yanerys, Rodriguez, Jason, Mazur, Marina, Birket, Susan E., Rowe, Steven M., West, Natalie E., Livraghi-Butrico, Alessandra, Boucher, Richard C., Hanes, Justin, Aslanidi, George, Suk, Jung Soo
Publicado no Mol Ther Methods Clin Dev (2018)

Novel Therapy of Bicarbonate, Glutathione, and Ascorbic Acid Improves Cystic Fibrosis Mucus Transport

Por Adewale, Adegboyega Timothy, Falk Libby, Emily, Fu, Lianwu, Lenzie, Andrew, Boitet, Evan R., Birket, Susan E., Petty, Courtney Fernandez, Johns, J. Dixon, Mazur, Marina, Tearney, Guillermo J., Copeland, Dan, Durham, Carolyn, Rowe, Steven M.
Publicado no Am J Respir Cell Mol Biol (2020)

A Pharmacologic Approach to Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction in Smoking Related Lung Disease

Por Sloane, Peter A., Shastry, Suresh, Wilhelm, Andrew, Courville, Clifford, Tang, Li Ping, Backer, Kyle, Levin, Elina, Raju, S. Vamsee, Li, Yao, Mazur, Marina, Byan-Parker, Suzanne, Grizzle, William, Sorscher, Eric J., Dransfield, Mark T., Rowe, Steven M.
Publicado em 2012

Cystic Fibrosis Transmembrane Conductance Regulator Activation by Roflumilast Contributes to Therapeutic Benefit in Chronic Bronchitis

Por Lambert, James A., Raju, S. Vamsee, Tang, Li Ping, McNicholas, Carmel M., Li, Yao, Courville, Clifford A., Farris, Roopan F., Coricor, George E., Smoot, Lisa H., Mazur, Marina M., Dransfield, Mark T., Bolger, Graeme B., Rowe, Steven M.
Publicado em 2014

Method for Quantitative Study of Airway Functional Microanatomy Using Micro-Optical Coherence Tomography

Por Liu, Linbo, Chu, Kengyeh K., Houser, Grace H., Diephuis, Bradford J., Li, Yao, Wilsterman, Eric J., Shastry, Suresh, Dierksen, Gregory, Birket, Susan E., Mazur, Marina, Byan-Parker, Suzanne, Grizzle, William E., Sorscher, Eric J., Rowe, Steven M., Tearney, Guillermo J.
Publicado em 2013

Combination therapy with cystic fibrosis transmembrane conductance regulator modulators augment the airway functional microanatomy

Por Birket, Susan E., Chu, Kengyeh K., Houser, Grace H., Liu, Linbo, Fernandez, Courtney M., Solomon, George M., Lin, Vivian, Shastry, Suresh, Mazur, Marina, Sloane, Peter A., Hanes, Justin, Grizzle, William E., Sorscher, Eric J., Tearney, Guillermo J., Rowe, Steven M.
Publicado no Am J Physiol Lung Cell Mol Physiol (2016)

Discovery of Clinically Approved Agents That Promote Suppression of Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations

Por Mutyam, Venkateshwar, Du, Ming, Xue, Xiaojiao, Keeling, Kim M., White, E. Lucile, Bostwick, J. Robert, Rasmussen, Lynn, Liu, Bo, Mazur, Marina, Hong, Jeong S., Falk Libby, Emily, Liang, Feng, Shang, Haibo, Mense, Martin, Suto, Mark J., Bedwell, David M., Rowe, Steven M.
Publicado no Am J Respir Crit Care Med (2016)

Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule The...

Por Chung, W. Joon, Goeckeler-Fried, Jennifer L., Havasi, Viktoria, Chiang, Annette, Rowe, Steven M., Plyler, Zackery E., Hong, Jeong S., Mazur, Marina, Piazza, Gary A., Keeton, Adam B., White, E. Lucile, Rasmussen, Lynn, Weissman, Allan M., Denny, R. Aldrin, Brodsky, Jeffrey L., Sorscher, Eric J.
Publicado no PLoS One (2016)

A Functional Anatomic Defect of the Cystic Fibrosis Airway

Por Birket, Susan E., Chu, Kengyeh K., Liu, Linbo, Houser, Grace H., Diephuis, Bradford J., Wilsterman, Eric J., Dierksen, Gregory, Mazur, Marina, Shastry, Suresh, Li, Yao, Watson, John D., Smith, Alexander T., Schuster, Benjamin S., Hanes, Justin, Grizzle, William E., Sorscher, Eric J., Tearney, Guillermo J., Rowe, Steven M.
Publicado em 2014

The Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Ivacaftor Augments Mucociliary Clearance Abrogating Cystic Fibrosis Transmembrane Conductance Regulator Inhibiti...

Por Raju, S. Vamsee, Lin, Vivian Y., Liu, Limbo, McNicholas, Carmel M., Karki, Suman, Sloane, Peter A., Tang, Liping, Jackson, Patricia L., Wang, Wei, Wilson, Landon, Macon, Kevin J., Mazur, Marina, Kappes, John C., DeLucas, Lawrence J., Barnes, Stephen, Kirk, Kevin, Tearney, Guillermo J., Rowe, Steven M.
Publicado no Am J Respir Cell Mol Biol (2017)

A glycopolymer improves vascoelasticity and mucociliary transport of abnormal cystic fibrosis mucus

Por Fernandez-Petty, Courtney M., Hughes, Gareth W., Bowers, Hannah L., Watson, John D., Rosen, Bradley H., Townsend, Stacy M., Santos, Carlo, Ridley, Caroline E., Chu, Kengyeh K., Birket, Susan E., Li, Yao, Leung, Hui Min, Mazur, Marina, Garcia, Bryan A., Evans, T. Idil Apak, Libby, Emily Falk, Hathorne, Heather, Hanes, Justin, Tearney, Guillermo J., Clancy, John P., Engelhardt, John F., Swords, William E., Thornton, David J., Wiesmann, William P., Baker, Shenda M., Rowe, Steven M.
Publicado no JCI Insight (2019)