Beyond cystic fibrosis transmembrane conductance regulator (CFTR) single channel kinetics: implications for therapeutic intervention

Por McNicholas, Carmel M.
Publicado no J Physiol (2017)

Diversity of Channels Generated by Different Combinations of Epithelial Sodium Channel Subunits

Por McNicholas, Carmel M., Canessa, Cecilia M.
Publicado em 1997

Phosphatidylinositol 4,5-bisphosphate (PIP(2)) stimulates the electrogenic Na/HCO(3) cotransporter NBCe1-A expressed in Xenopus oocytes

Por Wu, Jianping, McNicholas, Carmel M., Bevensee, Mark O.
Publicado em 2009

Physical and functional interactions between a glioma cation channel and integrin-β(1) require α-actinin

Por Rooj, Arun K., Liu, Zhiyong, McNicholas, Carmel M., Fuller, Catherine M.
Publicado no Am J Physiol Cell Physiol (2015)

Glioma-specific Cation Conductance Regulates Migration and Cell Cycle Progression

Por Rooj, Arun K., McNicholas, Carmel M., Bartoszewski, Rafal, Bebok, Zsuzsanna, Benos, Dale J., Fuller, Catherine M.
Publicado em 2012

Expression and Purification of the Alpha Subunit of the Epithelial Sodium Channel, ENaC

Por Reddy, Bharat G., Dai, Qun, McNicholas, Carmel M., Fuller, Catherine M., Kappes, John C., DeLucas, Lawrence J.
Publicado no Protein Expr Purif (2015)

Resveratrol Enhances Airway Surface Liquid Depth in Sinonasal Epithelium by Increasing Cystic Fibrosis Transmembrane Conductance Regulator Open Probability

Por Zhang, Shaoyan, Blount, Angela C., McNicholas, Carmel M., Skinner, Daniel F., Chestnut, Michael, Kappes, John C., Sorscher, Eric J., Woodworth, Bradford A.
Publicado em 2013

Correction: Resveratrol Enhances Airway Surface Liquid Depth in Sinonasal Epithelium by Increasing Cystic Fibrosis Transmembrane Conductance Regulator Open Probability

Por Zhang, Shaoyan, Blount, Angela C., McNicholas, Carmel M., Skinner, Daniel F., Chestnut, Michael, Kappes, John C., Sorscher, Eric J., Woodworth, Bradford A.
Publicado em 2014

Sinupret Activates CFTR and TMEM16A-Dependent Transepithelial Chloride Transport and Improves Indicators of Mucociliary Clearance

Por Zhang, Shaoyan, Skinner, Daniel, Hicks, Stephen Bradley, Bevensee, Mark O., Sorscher, Eric J., Lazrak, Ahmed, Matalon, Sadis, McNicholas, Carmel M., Woodworth, Bradford A.
Publicado em 2014

IL-8 inhibits cAMP-stimulated alveolar epithelial fluid transport via a GRK2/PI3K-dependent mechanism

Por Roux, Jérémie, McNicholas, Carmel M., Carles, Michel, Goolaerts, Arnaud, Houseman, Benjamin T., Dickinson, Dale A., Iles, Karen E., Ware, Lorraine B., Matthay, Michael A., Pittet, Jean-François
Publicado em 2013

Interaction of ASIC1 and ENaC subunits in human glioma cells and rat astrocytes

Por Kapoor, Niren, Lee, William, Clark, Edlira, Bartoszewski, Rafal, McNicholas, Carmel M., Latham, Cecelia B., Bebok, Zsuzsanna, Parpura, Vladimir, Fuller, Catherine M., Palmer, Cheryl A., Benos, Dale J.
Publicado em 2011

Analysis of cystic fibrosis–associated P67L CFTR illustrates barriers to personalized therapeutics for orphan diseases

Por Sabusap, Carleen M., Wang, Wei, McNicholas, Carmel M., Chung, W. Joon, Fu, Lianwu, Wen, Hui, Mazur, Marina, Kirk, Kevin L., Collawn, James F., Hong, Jeong S., Sorscher, Eric J.
Publicado no JCI Insight (2016)

Cystic Fibrosis Transmembrane Conductance Regulator Activation by Roflumilast Contributes to Therapeutic Benefit in Chronic Bronchitis

Por Lambert, James A., Raju, S. Vamsee, Tang, Li Ping, McNicholas, Carmel M., Li, Yao, Courville, Clifford A., Farris, Roopan F., Coricor, George E., Smoot, Lisa H., Mazur, Marina M., Dransfield, Mark T., Bolger, Graeme B., Rowe, Steven M.
Publicado em 2014

An Aberrant Leukotriene A(4) Hydrolase–Proline-Glycine-Proline Pathway in the Pathogenesis of Chronic Obstructive Pulmonary Disease

Por Wells, J. Michael, O’Reilly, Philip J., Szul, Tomasz, Sullivan, Daniel I., Handley, Guy, Garrett, Chris, McNicholas, Carmel M., Roda, Mojtaba Abdul, Miller, Bruce E., Tal-Singer, Ruth, Gaggar, Amit, Rennard, Stephen I., Jackson, Patricia L., Blalock, J. Edwin
Publicado no Am J Respir Crit Care Med (2014)

The Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Ivacaftor Augments Mucociliary Clearance Abrogating Cystic Fibrosis Transmembrane Conductance Regulator Inhibiti...

Por Raju, S. Vamsee, Lin, Vivian Y., Liu, Limbo, McNicholas, Carmel M., Karki, Suman, Sloane, Peter A., Tang, Liping, Jackson, Patricia L., Wang, Wei, Wilson, Landon, Macon, Kevin J., Mazur, Marina, Kappes, John C., DeLucas, Lawrence J., Barnes, Stephen, Kirk, Kevin, Tearney, Guillermo J., Rowe, Steven M.
Publicado no Am J Respir Cell Mol Biol (2017)

Cigarette Smoke Induces Systemic Defects in Cystic Fibrosis Transmembrane Conductance Regulator Function

Por Raju, S. Vamsee, Jackson, Patricia L., Courville, Clifford A., McNicholas, Carmel M., Sloane, Peter A., Sabbatini, Gina, Tidwell, Sherry, Tang, Li Ping, Liu, Bo, Fortenberry, James A., Jones, Caleb W., Boydston, Jeremy A., Clancy, J. P., Bowen, Larry E., Accurso, Frank J., Blalock, J. Edwin, Dransfield, Mark T., Rowe, Steven M.
Publicado em 2013