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Sinupret Activates CFTR and TMEM16A-Dependent Transepithelial Chloride Transport and Improves Indicators of Mucociliary Clearance

INTRODUCTION: We have previously demonstrated that Sinupret, an established treatment prescribed widely in Europe for respiratory ailments including rhinosinusitis, promotes transepithelial chloride (Cl(−)) secretion in vitro and in vivo. The present study was designed to evaluate other indicators o...

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Autores principales: Zhang, Shaoyan, Skinner, Daniel, Hicks, Stephen Bradley, Bevensee, Mark O., Sorscher, Eric J., Lazrak, Ahmed, Matalon, Sadis, McNicholas, Carmel M., Woodworth, Bradford A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130514/
https://ncbi.nlm.nih.gov/pubmed/25117505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104090
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