Being positive: revisiting the elevated sodium permeability hypothesis in cystic fibrosis

gan Kirk, Kevin L
Cyhoeddwyd 2013

A Unified View of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gating: Combining the Allosterism of a Ligand-gated Channel with the Enzymatic Activity of an ATP-bindi...

gan Kirk, Kevin L., Wang, Wei
Cyhoeddwyd 2011

Cross-linking of F508-CFTR promotes its trafficking to the plasma membrane

gan Bernard, Karen, Kirk, Kevin L
Cyhoeddwyd 2010

The CFTR Ion Channel: Gating, Regulation, and Anion Permeation

gan Hwang, Tzyh-Chang, Kirk, Kevin L.
Cyhoeddwyd 2013

An Electrostatic Interaction at the Tetrahelix Bundle Promotes Phosphorylation-dependent Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Channel Opening

gan Wang, Wei, Roessler, Bryan C., Kirk, Kevin L.
Cyhoeddwyd 2014

Converting Nonhydrolyzable Nucleotides to Strong Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Agonists by Gain of Function (GOF) Mutations

gan Okeyo, George, Wang, Wei, Wei, Shipeng, Kirk, Kevin L.
Cyhoeddwyd 2013

A cluster of negative charges at the amino terminal tail of CFTR regulates ATP-dependent channel gating

gan Fu, Jian, Ji, Hong-Long, Naren, Anjaparavanda P, Kirk, Kevin L
Cyhoeddwyd 2001

Accuracy of Posterior Subtalar Joint Injection Without Fluoroscopy

gan Kirk, Kevin L., Campbell, John T., Guyton, Gregory P., Schon, Lew C.
Cyhoeddwyd 2008

Curcumin Cross-links Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Polypeptides and Potentiates CFTR Channel Activity by Distinct Mechanisms

gan Bernard, Karen, Wang, Wei, Narlawar, Rajeshwar, Schmidt, Boris, Kirk, Kevin L.
Cyhoeddwyd 2009

CFTR surface expression and chloride currents are decreased by inhibitors of N-WASP and actin polymerization

gan Ganeshan, Radhika, Nowotarski, Krzysztof, Di, Anke, Nelson, Deborah J., Kirk, Kevin L.
Cyhoeddwyd 2006

Thermally Unstable Gating of the Most Common Cystic Fibrosis Mutant Channel (ΔF508): “RESCUE” BY SUPPRESSOR MUTATIONS IN NUCLEOTIDE BINDING DOMAIN 1 AND BY CONSTITUTIVE MUTATIONS I...

gan Wang, Wei, Okeyo, George O., Tao, Binli, Hong, Jeong S., Kirk, Kevin L.
Cyhoeddwyd 2011

Robust Stimulation of W1282X-CFTR Channel Activity by a Combination of Allosteric Modulators

gan Wang, Wei, Hong, Jeong S., Rab, Andras, Sorscher, Eric J., Kirk, Kevin L.
Cyhoeddwyd yn PLoS One (2016)

Reversible Silencing of CFTR Chloride Channels by Glutathionylation

gan Wang, Wei, Oliva, Claudia, Li, Ge, Holmgren, Arne, Lillig, Christopher Horst, Kirk, Kevin L.
Cyhoeddwyd 2005

Syntaxin 1A inhibits CFTR chloride channels by means of domain-specific protein–protein interactions

gan Naren, Anjaparavanda P., Quick, Michael W., Collawn, James F., Nelson, Deborah J., Kirk, Kevin L.
Cyhoeddwyd 1998

Conserved Allosteric Hot Spots in the Transmembrane Domains of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Channels and Multidrug Resistance Protein (MRP) Pumps

gan Wei, Shipeng, Roessler, Bryan C., Chauvet, Sylvain, Guo, Jingyu, Hartman, John L., Kirk, Kevin L.
Cyhoeddwyd 2014

ATP-independent CFTR channel gating and allosteric modulation by phosphorylation

gan Wang, Wei, Wu, Jianping, Bernard, Karen, Li, Ge, Wang, Guangyu, Bevensee, Mark O., Kirk, Kevin L.
Cyhoeddwyd 2010

Rescuing cystic fibrosis transmembrane conductance regulator (CFTR)-processing mutants by transcomplementation

gan Cormet-Boyaka, Estelle, Jablonsky, Michael, Naren, Anjaparavanda P., Jackson, Patricia L., Muccio, Donald D., Kirk, Kevin L.
Cyhoeddwyd 2004

Long-range coupling between the extracellular gates and the intracellular ATP binding domains of multidrug resistance protein pumps and cystic fibrosis transmembrane conductance re...

gan Wei, Shipeng, Roessler, Bryan C., Icyuz, Mert, Chauvet, Sylvain, Tao, Binli, Hartman, John L., Kirk, Kevin L.
Cyhoeddwyd yn FASEB J (2015)

G551D mutation impairs PKA-dependent activation of CFTR channel that can be restored by novel GOF mutations

gan Wang, Wei, Fu, Lianwu, Liu, Zhiyong, Wen, Hui, Rab, Andras, Hong, Jeong S., Kirk, Kevin L., Rowe, Steven M.
Cyhoeddwyd yn Am J Physiol Lung Cell Mol Physiol (2020)

CFTR chloride channels are regulated by a SNAP-23/syntaxin 1A complex

gan Cormet-Boyaka, Estelle, Di, Anke, Chang, Steven Y., Naren, Anjaparavanda P., Tousson, Albert, Nelson, Deborah J., Kirk, Kevin L.
Cyhoeddwyd 2002