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The CFTR Ion Channel: Gating, Regulation, and Anion Permeation

Cystic fibrosis transmembrane conductance regulator (CFTR) is an ATP-gated anion channel with two remarkable distinctions. First, it is the only ATP-binding cassette (ABC) transporter that is known to be an ion channel—almost all others function as transport ATPases. Second, CFTR is the only ligand-...

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Detalhes bibliográficos
Main Authors: Hwang, Tzyh-Chang, Kirk, Kevin L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530039/
https://ncbi.nlm.nih.gov/pubmed/23284076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a009498
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