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The CFTR Ion Channel: Gating, Regulation, and Anion Permeation
Cystic fibrosis transmembrane conductance regulator (CFTR) is an ATP-gated anion channel with two remarkable distinctions. First, it is the only ATP-binding cassette (ABC) transporter that is known to be an ion channel—almost all others function as transport ATPases. Second, CFTR is the only ligand-...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530039/ https://ncbi.nlm.nih.gov/pubmed/23284076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a009498 |
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