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Cysteine Scanning of CFTR’s First Transmembrane Segment Reveals Its Plausible Roles in Gating and Permeation

Previous cysteine scanning studies of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel have identified several transmembrane segments (TMs), including TM1, 3, 6, 9, and 12, as structural components of the pore. Some of these TMs such as TM6 and 12 may also be involved...

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Bibliografski detalji
Glavni autori: Gao, Xiaolong, Bai, Yonghong, Hwang, Tzyh-Chang
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576531/
https://ncbi.nlm.nih.gov/pubmed/23442957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.048
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