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The Fifth Transmembrane Segment of Cystic Fibrosis Transmembrane Conductance Regulator Contributes to Its Anion Permeation Pathway

Previous studies have identified several transmembrane segments (TMs), including TM1, TM3, TM6, TM9, TM11, and TM12, as pore-lining segments in cystic fibrosis transmembrane conductance regulator (CFTR), but the role of TM5 in pore construction remains controversial. In this study, we employed subst...

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Vydáno v:Biochemistry
Hlavní autoři: Zhang, Jingyao, Hwang, Tzyh-Chang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510985/
https://ncbi.nlm.nih.gov/pubmed/26024338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00427
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