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The Fifth Transmembrane Segment of Cystic Fibrosis Transmembrane Conductance Regulator Contributes to Its Anion Permeation Pathway

Previous studies have identified several transmembrane segments (TMs), including TM1, TM3, TM6, TM9, TM11, and TM12, as pore-lining segments in cystic fibrosis transmembrane conductance regulator (CFTR), but the role of TM5 in pore construction remains controversial. In this study, we employed subst...

詳細記述

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書誌詳細
出版年:Biochemistry
主要な著者: Zhang, Jingyao, Hwang, Tzyh-Chang
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510985/
https://ncbi.nlm.nih.gov/pubmed/26024338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00427
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