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Modulation of CFTR gating by permeant ions

Cystic fibrosis transmembrane conductance regulator (CFTR) is unique among ion channels in that after its phosphorylation by protein kinase A (PKA), its ATP-dependent gating violates microscopic reversibility caused by the intimate involvement of ATP hydrolysis in controlling channel closure. Recent...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Yeh, Han-I, Yeh, Jiunn-Tyng, Hwang, Tzyh-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278182/
https://ncbi.nlm.nih.gov/pubmed/25512598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411272
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