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Structural mechanisms of CFTR function and dysfunction
Cystic fibrosis (CF) transmembrane conductance regulator (CFTR) chloride channel plays a critical role in regulating transepithelial movement of water and electrolyte in exocrine tissues. Malfunction of the channel because of mutations of the cftr gene results in CF, the most prevalent lethal geneti...
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| Publicado no: | J Gen Physiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5881446/ https://ncbi.nlm.nih.gov/pubmed/29581173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201711946 |
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