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Functional characterization reveals that zebrafish CFTR prefers to occupy closed channel conformations
Cystic fibrosis transmembrane conductance regulator (CFTR), the culprit behind the genetic disease cystic fibrosis (CF), is a phosphorylation-activated, but ATP-gated anion channel. Studies of human CFTR over the past two decades have provided an in-depth understanding of how CFTR works as an ion ch...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6312236/ https://ncbi.nlm.nih.gov/pubmed/30596737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209862 |
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