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Positional effects of premature termination codons on the biochemical and biophysical properties of CFTR

About one-third of genetic diseases and cancers are caused by the introduction of premature termination codon (PTC). In theory, the location of the PTC in a gene determines the alternative mechanisms of translation, including premature cessation or reinitiation of translation, and read-through, resu...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Physiol
Main Authors: Yeh, Jiunn-Tyng, Hwang, Tzyh-Chang
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087279/
https://ncbi.nlm.nih.gov/pubmed/31585024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP278418
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