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Positional effects of premature termination codons on the biochemical and biophysical properties of CFTR
About one-third of genetic diseases and cancers are caused by the introduction of premature termination codon (PTC). In theory, the location of the PTC in a gene determines the alternative mechanisms of translation, including premature cessation or reinitiation of translation, and read-through, resu...
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| Publicat a: | J Physiol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8087279/ https://ncbi.nlm.nih.gov/pubmed/31585024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP278418 |
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