Long-range coupling between the extracellular gates and the intracellular ATP binding domains of multidrug resistance protein pumps and cystic fibrosis transmembrane conductance regulator channels

The ABCC transporter subfamily includes pumps, the long and short multidrug resistance proteins (MRPs), and an ATP-gated anion channel, the cystic fibrosis transmembrane conductance regulator (CFTR). We show that despite their thermodynamic differences, these ABCC transporter subtypes use broadly si...

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Enregistré dans:
Détails bibliographiques
Publié dans:FASEB J
Auteurs principaux: Wei, Shipeng, Roessler, Bryan C., Icyuz, Mert, Chauvet, Sylvain, Tao, Binli, Hartman, John L., Kirk, Kevin L.
Format: Artigo
Langue:Inglês
Publié: Federation of American Societies for Experimental Biology 2015
Sujets:
Research Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750415/
https://ncbi.nlm.nih.gov/pubmed/26606940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-278382
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