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Role of ATP binding and hydrolysis in the gating of the cystic fibrosis transmembrane conductance regulator

The CFTR gene is unique within the ATP-binding cassette (ABC) protein family, predominantly of transporters, by coding a chloride channel. The gating mechanism of ABC proteins has been characterized by the ATP Switch model in terms cycles of dimer formation and dissociation linked to ATP binding and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile nagusia: Gout, Taras
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Medknow Publications & Media Pvt Ltd 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425041/
https://ncbi.nlm.nih.gov/pubmed/22924067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1817-1737.98842
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