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Cystic Fibrosis Transmembrane Conductance Regulator Activation by Roflumilast Contributes to Therapeutic Benefit in Chronic Bronchitis
Cigarette smoking causes acquired cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction and is associated with delayed mucociliary clearance and chronic bronchitis. Roflumilast is a clinically approved phosphodiesterase 4 inhibitor that improves lung function in patients with chroni...
में बचाया:
मुख्य लेखकों: | , , , , , , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
American Thoracic Society
2014
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4068936/ https://ncbi.nlm.nih.gov/pubmed/24106801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0228OC |
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