Cystic Fibrosis Transmembrane Conductance Regulator Activation by Roflumilast Contributes to Therapeutic Benefit in Chronic Bronchitis

Cigarette smoking causes acquired cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction and is associated with delayed mucociliary clearance and chronic bronchitis. Roflumilast is a clinically approved phosphodiesterase 4 inhibitor that improves lung function in patients with chroni...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Lambert, James A., Raju, S. Vamsee, Tang, Li Ping, McNicholas, Carmel M., Li, Yao, Courville, Clifford A., Farris, Roopan F., Coricor, George E., Smoot, Lisa H., Mazur, Marina M., Dransfield, Mark T., Bolger, Graeme B., Rowe, Steven M.
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2014
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068936/
https://ncbi.nlm.nih.gov/pubmed/24106801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0228OC
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires