The Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Ivacaftor Augments Mucociliary Clearance Abrogating Cystic Fibrosis Transmembrane Conductance Regulator Inhibition by Cigarette Smoke

Acquired cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction may contribute to chronic obstructive pulmonary disease pathogenesis and is a potential therapeutic target. We sought to determine the acute effects of cigarette smoke on ion transport and the mucociliary transport appar...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Am J Respir Cell Mol Biol
मुख्य लेखकों: Raju, S. Vamsee, Lin, Vivian Y., Liu, Limbo, McNicholas, Carmel M., Karki, Suman, Sloane, Peter A., Tang, Liping, Jackson, Patricia L., Wang, Wei, Wilson, Landon, Macon, Kevin J., Mazur, Marina, Kappes, John C., DeLucas, Lawrence J., Barnes, Stephen, Kirk, Kevin, Tearney, Guillermo J., Rowe, Steven M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Thoracic Society 2017
विषय:
Original Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248967/
https://ncbi.nlm.nih.gov/pubmed/27585394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0226OC
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