Activation of the Cystic Fibrosis Transmembrane Conductance Regulator by the Flavonoid Quercetin: Potential Use as a Biomarker of ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator Rescue

Therapies to correct the ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) folding defect require sensitive methods to detect channel activity in vivo. The β(2) adrenergic receptor agonists, which provide the CFTR stimuli commonly used in nasal potential difference assays, may not ove...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Pyle, Louise C., Fulton, Jennifer C., Sloane, Peter A., Backer, Kyle, Mazur, Marina, Prasain, Jeevan, Barnes, Stephen, Clancy, J. P., Rowe, Steven M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Thoracic Society 2010
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970857/
https://ncbi.nlm.nih.gov/pubmed/20042712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0281OC
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk