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Activation of the Cystic Fibrosis Transmembrane Conductance Regulator by the Flavonoid Quercetin: Potential Use as a Biomarker of ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator Rescue
Therapies to correct the ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) folding defect require sensitive methods to detect channel activity in vivo. The β(2) adrenergic receptor agonists, which provide the CFTR stimuli commonly used in nasal potential difference assays, may not ove...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Thoracic Society
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2970857/ https://ncbi.nlm.nih.gov/pubmed/20042712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0281OC |
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