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Activation of the Cystic Fibrosis Transmembrane Conductance Regulator by the Flavonoid Quercetin: Potential Use as a Biomarker of ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator Rescue

Therapies to correct the ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) folding defect require sensitive methods to detect channel activity in vivo. The β(2) adrenergic receptor agonists, which provide the CFTR stimuli commonly used in nasal potential difference assays, may not ove...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Pyle, Louise C., Fulton, Jennifer C., Sloane, Peter A., Backer, Kyle, Mazur, Marina, Prasain, Jeevan, Barnes, Stephen, Clancy, J. P., Rowe, Steven M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Thoracic Society 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970857/
https://ncbi.nlm.nih.gov/pubmed/20042712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0281OC
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