Combination therapy with cystic fibrosis transmembrane conductance regulator modulators augment the airway functional microanatomy

Recently approved therapies that modulate CFTR function have shown significant clinical benefit, but recent investigations regarding their molecular mechanism when used in combination have not been consistent with clinical results. We employed micro-optical coherence tomography as a novel means to a...

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Bibliographic Details
Published in:Am J Physiol Lung Cell Mol Physiol
Main Authors: Birket, Susan E., Chu, Kengyeh K., Houser, Grace H., Liu, Linbo, Fernandez, Courtney M., Solomon, George M., Lin, Vivian, Shastry, Suresh, Mazur, Marina, Sloane, Peter A., Hanes, Justin, Grizzle, William E., Sorscher, Eric J., Tearney, Guillermo J., Rowe, Steven M.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896103/
https://ncbi.nlm.nih.gov/pubmed/26968770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00395.2015
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