Combination therapy with cystic fibrosis transmembrane conductance regulator modulators augment the airway functional microanatomy

Recently approved therapies that modulate CFTR function have shown significant clinical benefit, but recent investigations regarding their molecular mechanism when used in combination have not been consistent with clinical results. We employed micro-optical coherence tomography as a novel means to a...

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Publicado en:Am J Physiol Lung Cell Mol Physiol
Autores principales: Birket, Susan E., Chu, Kengyeh K., Houser, Grace H., Liu, Linbo, Fernandez, Courtney M., Solomon, George M., Lin, Vivian, Shastry, Suresh, Mazur, Marina, Sloane, Peter A., Hanes, Justin, Grizzle, William E., Sorscher, Eric J., Tearney, Guillermo J., Rowe, Steven M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896103/
https://ncbi.nlm.nih.gov/pubmed/26968770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00395.2015
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