Combination therapy with cystic fibrosis transmembrane conductance regulator modulators augment the airway functional microanatomy

Recently approved therapies that modulate CFTR function have shown significant clinical benefit, but recent investigations regarding their molecular mechanism when used in combination have not been consistent with clinical results. We employed micro-optical coherence tomography as a novel means to a...

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Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: Birket, Susan E., Chu, Kengyeh K., Houser, Grace H., Liu, Linbo, Fernandez, Courtney M., Solomon, George M., Lin, Vivian, Shastry, Suresh, Mazur, Marina, Sloane, Peter A., Hanes, Justin, Grizzle, William E., Sorscher, Eric J., Tearney, Guillermo J., Rowe, Steven M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896103/
https://ncbi.nlm.nih.gov/pubmed/26968770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00395.2015
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