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Activation of the Unfolded Protein Response by ΔF508 CFTR
Environmental insults and misfolded proteins cause endoplasmic reticulum (ER) stress and activate the unfolded protein response (UPR). The UPR decreases endogenous cystic fibrosis transmembrane conductance regulator (CFTR) mRNA levels and protein maturation efficiency. Herein, we investigated the ef...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Thoracic Society
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2551705/ https://ncbi.nlm.nih.gov/pubmed/18458236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0065OC |
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