Activation of the Unfolded Protein Response by ΔF508 CFTR

Environmental insults and misfolded proteins cause endoplasmic reticulum (ER) stress and activate the unfolded protein response (UPR). The UPR decreases endogenous cystic fibrosis transmembrane conductance regulator (CFTR) mRNA levels and protein maturation efficiency. Herein, we investigated the ef...

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Detalhes bibliográficos
Main Authors: Bartoszewski, Rafal, Rab, Andras, Jurkuvenaite, Asta, Mazur, Marina, Wakefield, John, Collawn, James F., Bebők, Zsuzsa
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551705/
https://ncbi.nlm.nih.gov/pubmed/18458236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0065OC
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