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Rescuing ΔF508 CFTR with trimethylangelicin, a dual-acting corrector and potentiator
Since the discovery of the cystic fibrosis (CF) gene that encodes the CF transmembrane conductance regulator (CFTR) in 1989, there has been considerable progress in understanding the molecular defects associated with different mutations in the CFTR protein. Small molecule “potentiators” have led the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4166784/ https://ncbi.nlm.nih.gov/pubmed/25063802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00177.2014 |
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