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Rescuing ΔF508 CFTR with trimethylangelicin, a dual-acting corrector and potentiator
Since the discovery of the cystic fibrosis (CF) gene that encodes the CF transmembrane conductance regulator (CFTR) in 1989, there has been considerable progress in understanding the molecular defects associated with different mutations in the CFTR protein. Small molecule “potentiators” have led the...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Physiological Society
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4166784/ https://ncbi.nlm.nih.gov/pubmed/25063802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00177.2014 |
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