Novel Therapy of Bicarbonate, Glutathione, and Ascorbic Acid Improves Cystic Fibrosis Mucus Transport

Defective airway mucus clearance is a defining characteristic of cystic fibrosis lung disease, and improvements to current mucolytic strategies are needed. Novel approaches targeting a range of contributing mechanisms are in various stages of preclinical and clinical development. ARINA-1 is a new ne...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Adewale, Adegboyega Timothy, Falk Libby, Emily, Fu, Lianwu, Lenzie, Andrew, Boitet, Evan R., Birket, Susan E., Petty, Courtney Fernandez, Johns, J. Dixon, Mazur, Marina, Tearney, Guillermo J., Copeland, Dan, Durham, Carolyn, Rowe, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462336/
https://ncbi.nlm.nih.gov/pubmed/32374624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2019-0287OC
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