Excess mucus viscosity and airway dehydration impact COPD airway clearance

The mechanisms by which cigarette smoking impairs airway mucus clearance are not well understood. We recently established a ferret model of cigarette smoke-induced chronic obstructive pulmonary disease (COPD) exhibiting chronic bronchitis. We investigated the effects of cigarette smoke on mucociliar...

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Detalhes bibliográficos
Publicado no:Eur Respir J
Main Authors: Lin, Vivian Y., Kaza, Niroop, Birket, Susan E., Kim, Harrison, Edwards, Lloyd J., LaFontaine, Jennifer, Liu, Linbo, Mazur, Marina, Byzek, Stephen A., Hanes, Justin, Tearney, Guillermo J., Raju, S. Vamsee, Rowe, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7336367/
https://ncbi.nlm.nih.gov/pubmed/31672759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.00419-2019
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