A glycopolymer improves vascoelasticity and mucociliary transport of abnormal cystic fibrosis mucus

Cystic fibrosis (CF) is characterized by increased mucus viscosity and delayed mucociliary clearance that contributes to progressive decline of lung function. Mucus in the respiratory and GI tract is excessively adhesive in the presence of airway dehydration and excess extracellular Ca(2+) upon muci...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:JCI Insight
المؤلفون الرئيسيون: Fernandez-Petty, Courtney M., Hughes, Gareth W., Bowers, Hannah L., Watson, John D., Rosen, Bradley H., Townsend, Stacy M., Santos, Carlo, Ridley, Caroline E., Chu, Kengyeh K., Birket, Susan E., Li, Yao, Leung, Hui Min, Mazur, Marina, Garcia, Bryan A., Evans, T. Idil Apak, Libby, Emily Falk, Hathorne, Heather, Hanes, Justin, Tearney, Guillermo J., Clancy, John P., Engelhardt, John F., Swords, William E., Thornton, David J., Wiesmann, William P., Baker, Shenda M., Rowe, Steven M.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Clinical Investigation 2019
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538343/
https://ncbi.nlm.nih.gov/pubmed/30996141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125954
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