Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol

Por Breckenridge, David G., Stojanovic, Marina, Marcellus, Richard C., Shore, Gordon C.
Publicado em 2003

Analysis of Synthesis, Stability, Phosphorylation, and Interacting Polypeptides of the 34-Kilodalton Product of Open Reading Frame 6 of the Early Region 4 Protein of Human Adenov...

Por Boivin, Dominique, Morrison, Megan R., Marcellus, Richard C., Querido, Emmanuelle, Branton, Philip E.
Publicado em 1999

Induction of p53-Independent Apoptosis by the Adenovirus E4orf4 Protein Requires Binding to the Bα Subunit of Protein Phosphatase 2A

Por Marcellus, Richard C., Chan, Helen, Paquette, Denis, Thirlwell, Sarah, Boivin, Dominique, Branton, Philip E.
Publicado em 2000

BID-D59A is a potent inducer of apoptosis in primary embryonic fibroblasts.

Por Sarig, Rachel, Zaltsman, Yehudit, Marcellus, Richard C., Flavell, Richard, Mak, Tak W., Gross, Atan
Publicado em 2012

BID-D59A is a potent inducer of apoptosis in primary embryonic fibroblasts.

Por Sarig, Rachel, Zaltsman, Yehudit, Marcellus, Richard C., Flavell, Richard, Mak, Tak W., Gross, Atan
Publicado em 2013

The Early Region 4 orf4 Protein of Human Adenovirus Type 5 Induces p53-Independent Cell Death by Apoptosis

Por Marcellus, Richard C., Lavoie, Josée N., Boivin, Dominique, Shore, Gordon C., Ketner, Gary, Branton, Philip E.
Publicado em 1998

Interaction between the Human Mitochondrial Import Receptors Tom20 and Tom70 in Vitro Suggests a Chaperone Displacement Mechanism

Por Fan, Anna C. Y., Kozlov, Guennadi, Hoegl, Annabelle, Marcellus, Richard C., Wong, Michael J. H., Gehring, Kalle, Young, Jason C.
Publicado em 2011

Genetic Analysis of B55α/Cdc55 Protein Phosphatase 2A Subunits: Association with the Adenovirus E4orf4 Protein

Por Zhang, Zhiying, Mui, Melissa Z., Chan, Francine, Roopchand, Diana E., Marcellus, Richard C., Blanchette, Paola, Li, Suiyang, Berghuis, Albert M., Branton, Philip E.
Publicado em 2011

The Adenovirus E4orf4 Protein Induces G(2)/M Arrest and Cell Death by Blocking Protein Phosphatase 2A Activity Regulated by the B55 Subunit

Por Li, Suiyang, Brignole, Claudine, Marcellus, Richard, Thirlwell, Sara, Binda, Olivier, McQuoid, Monica J., Ashby, Danita, Chan, Helen, Zhang, Zhiying, Miron, Marie-Joëlle, Pallas, David C., Branton, Philip E.
Publicado em 2009

Identification of RSK and TTK as Modulators of Blood Vessel Morphogenesis Using an Embryonic Stem Cell-Based Vascular Differentiation Assay

Por Hammoud, Lamis, Adams, Jessica R., Loch, Amanda J., Marcellus, Richard C., Uehling, David E., Aman, Ahmed, Fladd, Christopher, McKee, Trevor D., Jo, Christine E.B., Al-Awar, Rima, Egan, Sean E., Rossant, Janet
Publicado no Stem Cell Reports (2016)

Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer

Por Braunstein, Marsela, Liao, Linda, Lyttle, Nicola, Lobo, Nazleen, Taylor, Karen J., Krzyzanowski, Paul M., Kalatskaya, Irina, Yao, Cindy Q., Stein, Lincoln D., Boutros, Paul C., Twelves, Christopher J., Marcellus, Richard, Bartlett, John M. S., Spears, Melanie
Publicado no Breast Cancer Res (2016)

Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis

Por Nguyen, Mai, Marcellus, Richard C., Roulston, Anne, Watson, Mark, Serfass, Lucile, Murthy Madiraju, S. R., Goulet, Daniel, Viallet, Jean, Bélec, Laurent, Billot, Xavier, Acoca, Stephane, Purisima, Enrico, Wiegmans, Adrian, Cluse, Leonie, Johnstone, Ricky W., Beauparlant, Pierre, Shore, Gordon C.
Publicado em 2007

Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells

Por Grinshtein, Natalie, Rioseco, Constanza C., Marcellus, Richard, Uehling, David, Aman, Ahmed, Lun, Xueqing, Muto, Osamu, Podmore, Lauren, Lever, Jake, Shen, Yaoqing, Blough, Michael D., Cairncross, Greg J., Robbins, Stephen M., Jones, Steven J., Marra, Marco A., Al-Awar, Rima, Senger, Donna L., Kaplan, David R.
Publicado no Oncotarget (2016)

The Small Molecule GMX1778 Is a Potent Inhibitor of NAD(+) Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deficient Tumors

Por Watson, Mark, Roulston, Anne, Bélec, Laurent, Billot, Xavier, Marcellus, Richard, Bédard, Dominique, Bernier, Cynthia, Branchaud, Stéphane, Chan, Helen, Dairi, Kenza, Gilbert, Karine, Goulet, Daniel, Gratton, Michel-Olivier, Isakau, Henady, Jang, Anne, Khadir, Abdelkrim, Koch, Elizabeth, Lavoie, Manon, Lawless, Michael, Nguyen, Mai, Paquette, Denis, Turcotte, Émilie, Berger, Alvin, Mitchell, Matthew, Shore, Gordon C., Beauparlant, Pierre
Publicado em 2009

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

Por Grebien, Florian, Vedadi, Masoud, Getlik, Matthäus, Giambruno, Roberto, Grover, Amit, Avellino, Roberto, Skucha, Anna, Vittori, Sarah, Kuznetsova, Ekaterina, Smil, David, Barsyte-Lovejoy, Dalia, Li, Fengling, Poda, Gennadiy, Schapira, Matthieu, Wu, Hong, Dong, Aiping, Senisterra, Guillermo, Stukalov, Alexey, Huber, Kilian V. M., Schönegger, Andreas, Marcellus, Richard, Bilban, Martin, Bock, Christoph, Brown, Peter J., Zuber, Johannes, Bennett, Keiryn L., Al-awar, Rima, Delwel, Ruud, Nerlov, Claus, Arrowsmith, Cheryl H., Superti-Furga, Giulio
Publicado no Nat Chem Biol (2015)

(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells

Por Barsyte-Lovejoy, Dalia, Li, Fengling, Oudhoff, Menno J., Tatlock, John H., Dong, Aiping, Zeng, Hong, Wu, Hong, Freeman, Spencer A., Schapira, Matthieu, Senisterra, Guillermo A., Kuznetsova, Ekaterina, Marcellus, Richard, Allali-Hassani, Abdellah, Kennedy, Steven, Lambert, Jean-Philippe, Couzens, Amber L., Aman, Ahmed, Gingras, Anne-Claude, Al-Awar, Rima, Fish, Paul V., Gerstenberger, Brian S., Roberts, Lee, Benn, Caroline L., Grimley, Rachel L., Braam, Mitchell J. S., Rossi, Fabio M. V., Sudol, Marius, Brown, Peter J., Bunnage, Mark E., Owen, Dafydd R., Zaph, Colby, Vedadi, Masoud, Arrowsmith, Cheryl H.
Publicado em 2014