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Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer

BACKGROUND: Drug resistance in breast cancer is the major obstacle to effective treatment with chemotherapy. While upregulation of multidrug resistance genes is an important component of drug resistance mechanisms in vitro, their clinical relevance remains to be determined. Therefore, identifying pa...

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Bibliografiske detaljer
Udgivet i:Breast Cancer Res
Main Authors: Braunstein, Marsela, Liao, Linda, Lyttle, Nicola, Lobo, Nazleen, Taylor, Karen J., Krzyzanowski, Paul M., Kalatskaya, Irina, Yao, Cindy Q., Stein, Lincoln D., Boutros, Paul C., Twelves, Christopher J., Marcellus, Richard, Bartlett, John M. S., Spears, Melanie
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744406/
https://ncbi.nlm.nih.gov/pubmed/26852132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0676-6
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