Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer

BACKGROUND: Drug resistance in breast cancer is the major obstacle to effective treatment with chemotherapy. While upregulation of multidrug resistance genes is an important component of drug resistance mechanisms in vitro, their clinical relevance remains to be determined. Therefore, identifying pa...

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發表在:Breast Cancer Res
Main Authors: Braunstein, Marsela, Liao, Linda, Lyttle, Nicola, Lobo, Nazleen, Taylor, Karen J., Krzyzanowski, Paul M., Kalatskaya, Irina, Yao, Cindy Q., Stein, Lincoln D., Boutros, Paul C., Twelves, Christopher J., Marcellus, Richard, Bartlett, John M. S., Spears, Melanie
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744406/
https://ncbi.nlm.nih.gov/pubmed/26852132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0676-6
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