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ISOWN: accurate somatic mutation identification in the absence of normal tissue controls

BACKGROUND: A key step in cancer genome analysis is the identification of somatic mutations in the tumor. This is typically done by comparing the genome of the tumor to the reference genome sequence derived from a normal tissue taken from the same donor. However, there are a variety of common scenar...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Kalatskaya, Irina, Trinh, Quang M., Spears, Melanie, McPherson, John D., Bartlett, John M. S., Stein, Lincoln
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490163/
https://ncbi.nlm.nih.gov/pubmed/28659176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0446-9
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