The Adenovirus E4orf4 Protein Induces G(2)/M Arrest and Cell Death by Blocking Protein Phosphatase 2A Activity Regulated by the B55 Subunit

Human adenovirus E4orf4 protein is toxic in human tumor cells. Its interaction with the Bα subunit of protein phosphatase 2A (PP2A) is critical for cell killing; however, the effect of E4orf4 binding is not known. Bα is one of several mammalian B-type regulatory subunits that form PP2A holoenzymes w...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, Suiyang, Brignole, Claudine, Marcellus, Richard, Thirlwell, Sara, Binda, Olivier, McQuoid, Monica J., Ashby, Danita, Chan, Helen, Zhang, Zhiying, Miron, Marie-Joëlle, Pallas, David C., Branton, Philip E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2009
Pynciau:
Virus-Cell Interactions
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738146/
https://ncbi.nlm.nih.gov/pubmed/19535438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00711-09
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg