The role of the cytosolic HSP70 chaperone system in diseases caused by misfolding and aberrant trafficking of ion channels

per Young, Jason C.
Publicat 2014

Mechanisms of the Hsp70 chaperone system()

per Young, Jason C.
Publicat a Biochem Cell Biol (2010)

Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co-chaperone p23

per Young, Jason C., Hartl, F.Ulrich
Publicat 2000

Function of Cytosolic Chaperones in Tom70-Mediated Mitochondrial Import

per Fan, Anna C.Y., Young, Jason C.
Publicat a Protein Pept Lett (2011)

Hsp90: a specialized but essential protein-folding tool

per Young, Jason C., Moarefi, Ismail, Hartl, F. Ulrich
Publicat 2001

hERG quality control and the long QT syndrome

per Foo, Brian, Williamson, Brittany, Young, Jason C., Lukacs, Gergely, Shrier, Alvin
Publicat a J Physiol (2016)

Mitochondrial carrier protein biogenesis: role of the chaperones Hsc70 and Hsp90

per Zara, Vincenzo, Ferramosca, Alessandra, Robitaille-Foucher, Philippe, Palmieri, Ferdinando, Young, Jason C.
Publicat a Biochem J (2009)

Selective Binding of HSC70 and its Co-Chaperones to Structural Hotspots on CFTR

per Baaklini, Imad, Gonçalves, Conrado de Campos, Lukacs, Gergely L., Young, Jason C.
Publicat a Sci Rep (2020)

Functional Divergence between Co-chaperones of Hsc70()

per Tzankov, Stefan, Wong, Michael J. H., Shi, Kun, Nassif, Christina, Young, Jason C.
Publicat a J Biol Chem (2008)

Human mitochondrial import receptor Tom70 functions as a monomer

per Fan, Anna C. Y., Gava, Lisandra M., Ramos, Carlos H. I., Young, Jason C.
Publicat a Biochem J (2010)

Bag1 Co-chaperone Promotes TRC8 E3 Ligase-dependent Degradation of Misfolded Human Ether a Go-Go-related Gene (hERG) Potassium Channels

per Hantouche, Christine, Williamson, Brittany, Valinsky, William C., Solomon, Joshua, Shrier, Alvin, Young, Jason C.
Publicat a J Biol Chem (2017)

Membrane cholesterol as regulator of human rhomboid protease RHBDL4

per Paschkowsky, Sandra, Recinto, Sherilyn Junelle, Young, Jason C., Bondar, Ana-Nicoleta, Munter, Lisa Marie
Publicat a J Biol Chem (2018)

The DNAJA2 Substrate Release Mechanism Is Essential for Chaperone-mediated Folding

per Baaklini, Imad, Wong, Michael J. H., Hantouche, Christine, Patel, Yogita, Shrier, Alvin, Young, Jason C.
Publicat 2012

TARGETING AND INSERTION OF THE CHOLESTEROL-BINDING TRANSLOCATOR PROTEIN INTO THE OUTER MITOCHONDRIAL MEMBRANE

per Rone, Malena, Liu, Jun, Blonder, Josip, Ye, Xiaoying, Veenstra, Timothy D., Young, Jason C., Papadopoulos, Vassilios
Publicat 2009

Hsp40 Chaperones Promote Degradation of the hERG Potassium Channel

per Walker, Valerie E., Wong, Michael J. H., Atanasiu, Roxana, Hantouche, Christine, Young, Jason C., Shrier, Alvin
Publicat 2010

Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system

per Brychzy, Alexander, Rein, Theo, Winklhofer, Konstanze F., Hartl, F.Ulrich, Young, Jason C., Obermann, Wolfgang M.J.
Publicat 2003

Multiple 40-kDa Heat-Shock Protein Chaperones Function in Tom70-dependent Mitochondrial Import

per Bhangoo, Melanie K., Tzankov, Stefan, Fan, Anna C.Y., Dejgaard, Kurt, Thomas, David Y., Young, Jason C.
Publicat 2007

Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90

per Orthwein, Alexandre, Patenaude, Anne-Marie, Affar, El Bachir, Lamarre, Alain, Young, Jason C., Di Noia, Javier M.
Publicat 2010

A G protein–coupled receptor and the intracellular synthase of its agonist functionally cooperate

per Binda, Chantal, Génier, Samuel, Cartier, Andréane, Larrivée, Jean-François, Stankova, Jana, Young, Jason C., Parent, Jean-Luc
Publicat 2014

OEP61 is a chaperone receptor at the plastid outer envelope

per vonLoeffelholz, Ottilie, Kriechbaumer, Verena, Ewan, Richard A., Jonczyk, Rafal, Lehmann, Susann, Young, Jason C., Abell, Ben M.
Publicat a Biochem J (2011)