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The DNAJA2 Substrate Release Mechanism Is Essential for Chaperone-mediated Folding
DNAJA1 (DJA1/Hdj2) and DNAJA2 (DJA2) are the major J domain partners of human Hsp70/Hsc70 chaperones. Although they have overall similarity with the well characterized type I co-chaperones from yeast and bacteria, they are biologically distinct, and their functional mechanisms are poorly characteriz...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3516741/ https://ncbi.nlm.nih.gov/pubmed/23091061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.413278 |
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