A carregar...
Hsp70 and DNAJA2 limit CFTR levels through degradation
Cystic Fibrosis is caused by mutations in the CFTR anion channel, many of which cause its misfolding and degradation. CFTR folding depends on the Hsc70 and Hsp70 chaperones and their co-chaperone DNAJA1, but Hsc70/Hsp70 is also involved in CFTR degradation. Here, we address how these opposing functi...
Na minha lista:
| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6692068/ https://ncbi.nlm.nih.gov/pubmed/31408507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220984 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|