DnaJA1 antagonizes constitutive Hsp70-mediated stabilization of tau

Tau aggregation and amyloidogenesis are common hallmarks for neurodegenerative disorders called tauopathies. The molecular chaperone network constitutes the cellular defense against insults such as tau aggregation. However, chaperone effects on tau are dichotomous. Loss of tau’s microtubule-binding...

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Detaylı Bibliyografya
Asıl Yazarlar: Abisambra, Jose F., Jinwal, Umesh K., Suntharalingam, Amirthaa, Arulselvam, Karthik, Brady, Sarah, Cockman, Mattew, Jin, Ying, Zhang, Bo, Dickey, Chad A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371317/
https://ncbi.nlm.nih.gov/pubmed/22343013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.02.003
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