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DnaJA1 antagonizes constitutive Hsp70-mediated stabilization of tau
Tau aggregation and amyloidogenesis are common hallmarks for neurodegenerative disorders called tauopathies. The molecular chaperone network constitutes the cellular defense against insults such as tau aggregation. However, chaperone effects on tau are dichotomous. Loss of tau’s microtubule-binding...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3371317/ https://ncbi.nlm.nih.gov/pubmed/22343013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.02.003 |
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