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Imbalance of Hsp70 family variants fosters tau accumulation
Dysfunctional tau accumulation is a major contributing factor in tauopathies, and the heat-shock protein 70 (Hsp70) seems to play an important role in this accumulation. Several reports suggest that Hsp70 proteins can cause tau degradation to be accelerated or slowed, but how these opposing activiti...
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| Hlavní autoři: | , , , , , , , , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Federation of American Societies for Experimental Biology
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606536/ https://ncbi.nlm.nih.gov/pubmed/23271055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-220889 |
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