Proteomics-based Identification of Novel Factor Inhibiting Hypoxia-inducible Factor (FIH) Substrates Indicates Widespread Asparaginyl Hydroxylation of Ankyrin Repeat Domain-contain...

von Cockman, Matthew E., Webb, James D., Kramer, Holger B., Kessler, Benedikt M., Ratcliffe, Peter J.
Veröffentlicht 2009

Quantitative Mass Spectrometry Reveals Dynamics of Factor-inhibiting Hypoxia-inducible Factor-catalyzed Hydroxylation

von Singleton, Rachelle S., Trudgian, David C., Fischer, Roman, Kessler, Benedikt M., Ratcliffe, Peter J., Cockman, Matthew E.
Veröffentlicht 2011

Inherent DNA‐binding specificities of the HIF‐1α and HIF‐2α transcription factors in chromatin

von Smythies, James A, Sun, Min, Masson, Norma, Salama, Rafik, Simpson, Peter D, Murray, Elizabeth, Neumann, Viviana, Cockman, Matthew E, Choudhry, Hani, Ratcliffe, Peter J, Mole, David R
Veröffentlicht in EMBO Rep (2018)

Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding

von Thinnes, Cyrille C., Lohans, Christopher T., Abboud, Martine I., Yeh, Tzu‐Lan, Tumber, Anthony, Nowak, Radosław P., Attwood, Martin, Cockman, Matthew E., Oppermann, Udo, Loenarz, Christoph, Schofield, Christopher J.
Veröffentlicht in Chemistry (2019)

Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains

von Yang, Ming, Chowdhury, Rasheduzzaman, Ge, Wei, Hamed, Refaat B, McDonough, Michael A, Claridge, Timothy D W, Kessler, Benedikt M, Cockman, Matthew E, Ratcliffe, Peter J, Schofield, Christopher J
Veröffentlicht 2011

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates

von Cockman, Matthew E, Lippl, Kerstin, Tian, Ya-Min, Pegg, Hamish B, Figg, William D, Abboud, Martine I, Heilig, Raphael, Fischer, Roman, Myllyharju, Johanna, Schofield, Christopher J, Ratcliffe, Peter J
Veröffentlicht in eLife (2019)

Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy

von Loenarz, Christoph, Sekirnik, Rok, Thalhammer, Armin, Ge, Wei, Spivakovsky, Ekaterina, Mackeen, Mukram M., McDonough, Michael A., Cockman, Matthew E., Kessler, Benedikt M., Ratcliffe, Peter J., Wolf, Alexander, Schofield, Christopher J.
Veröffentlicht 2014

Glucose-regulated Protein 94 Triage of Mutant Myocilin through Endoplasmic Reticulum-associated Degradation Subverts a More Efficient Autophagic Clearance Mechanism

von Suntharalingam, Amirthaa, Abisambra, Jose F., O'Leary, John C., Koren, John, Zhang, Bo, Joe, Myung Kuk, Blair, Laura J., Hill, Shannon E., Jinwal, Umesh K., Cockman, Matthew, Duerfeldt, Adam S., Tomarev, Stanislav, Blagg, Brian S. J., Lieberman, Raquel L., Dickey, Chad A.
Veröffentlicht 2012

Tau Accumulation Activates the Unfolded Protein Response by Impairing Endoplasmic Reticulum-Associated Degradation

von Abisambra, Jose F., Jinwal, Umesh K., Blair, Laura J., O'Leary, John C., Li, Qingyou, Brady, Sarah, Wang, Li, Guidi, Chantal E., Zhang, Bo, Nordhues, Bryce A., Cockman, Matthew, Suntharalingham, Amirthaa, Li, Pengfei, Jin, Ying, Atkins, Christopher A., Dickey, Chad A.
Veröffentlicht 2013

Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

von Cockman, Matthew E., Lancaster, David E., Stolze, Ineke P., Hewitson, Kirsty S., McDonough, Michael A., Coleman, Mathew L., Coles, Charlotte H., Yu, Xiaohong, Hay, Ronald T., Ley, Steven C., Pugh, Christopher W., Oldham, Neil J., Masson, Norma, Schofield, Christopher J., Ratcliffe, Peter J.
Veröffentlicht 2006

Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth

von Katz, Maximiliano J., Acevedo, Julieta M., Loenarz, Christoph, Galagovsky, Diego, Liu-Yi, Phebee, Pérez-Pepe, Marcelo, Thalhammer, Armin, Sekirnik, Rok, Ge, Wei, Melani, Mariana, Thomas, María G., Simonetta, Sergio, Boccaccio, Graciela L., Schofield, Christopher J., Cockman, Matthew E., Ratcliffe, Peter J., Wappner, Pablo
Veröffentlicht 2014

OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation

von Singleton, Rachelle S., Liu-Yi, Phebee, Formenti, Fabio, Ge, Wei, Sekirnik, Rok, Fischer, Roman, Adam, Julie, Pollard, Patrick J., Wolf, Alexander, Thalhammer, Armin, Loenarz, Christoph, Flashman, Emily, Yamamoto, Atsushi, Coleman, Mathew L., Kessler, Benedikt M., Wappner, Pablo, Schofield, Christopher J., Ratcliffe, Peter J., Cockman, Matthew E.
Veröffentlicht 2014

Imbalance of Hsp70 family variants fosters tau accumulation

von Jinwal, Umesh K., Akoury, Elias, Abisambra, Jose F., O'Leary, John C., Thompson, Andrea D., Blair, Laura J., Jin, Ying, Bacon, Justin, Nordhues, Bryce A., Cockman, Matthew, Zhang, Juan, Li, Pengfei, Zhang, Bo, Borysov, Sergiy, Uversky, Vladimir N., Biernat, Jacek, Mandelkow, Eckhard, Gestwicki, Jason E., Zweckstetter, Markus, Dickey, Chad A.
Veröffentlicht 2013

Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau

von Abisambra, Jose, Jinwal, Umesh K., Miyata, Yoshinari, Rogers, Justin, Blair, Laura, Li, Xiaokai, Seguin, Sandlin P., Wang, Li, Jin, Ying, Bacon, Justin, Brady, Sarah, Cockman, Matthew, Guidi, Chantal, Zhang, Juan, Koren, John, Young, Zapporah T., Atkins, Christopher A., Zhang, Bo, Lawson, Lisa Y., Weeber, Edwin J., Brodsky, Jeffrey L., Gestwicki, Jason E., Dickey, Chad A.
Veröffentlicht 2013

Optimal Translational Termination Requires C4 Lysyl Hydroxylation of eRF1

von Feng, Tianshu, Yamamoto, Atsushi, Wilkins, Sarah E., Sokolova, Elizaveta, Yates, Luke A., Münzel, Martin, Singh, Pooja, Hopkinson, Richard J., Fischer, Roman, Cockman, Matthew E., Shelley, Jake, Trudgian, David C., Schödel, Johannes, McCullagh, James S.O., Ge, Wei, Kessler, Benedikt M., Gilbert, Robert J., Frolova, Ludmila Y., Alkalaeva, Elena, Ratcliffe, Peter J., Schofield, Christopher J., Coleman, Mathew L.
Veröffentlicht 2014

A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism

von Paolini, Nahuel A., Attwood, Martin, Sondalle, Samuel B., Vieira, Carolina Marques dos Santos, van Adrichem, Anita M., di Summa, Franca M., O’Donohue, Marie-Françoise, Gleizes, Pierre-Emmanuel, Rachuri, Swaksha, Briggs, Joseph W., Fischer, Roman, Ratcliffe, Peter J., Wlodarski, Marcin W., Houtkooper, Riekelt H., von Lindern, Marieke, Kuijpers, Taco W., Dinman, Jonathan D., Baserga, Susan J., Cockman, Matthew E., MacInnes, Alyson W.
Veröffentlicht in Am J Hum Genet (2017)

The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases

von Markolovic, Suzana, Zhuang, Qinqin, Wilkins, Sarah E, Eaton, Charlotte D, Abboud, Martine I, Katz, Maximiliano J, McNeil, Helen E, Leśniak, Robert K, Hall, Charlotte, Struwe, Weston B, Konietzny, Rebecca, Davis, Simon, Yang, Ming, Ge, Wei, Benesch, Justin LP, Kessler, Benedikt M, Ratcliffe, Peter J, Cockman, Matthew E, Fischer, Roman, Wappner, Pablo, Chowdhury, Rasheduzzaman, Coleman, Mathew L, Schofield, Christopher J
Veröffentlicht in Nat Chem Biol (2018)

Oxygenase Catalysed Ribosome Hydroxylation Occurs in Prokaryotes and Humans

von Ge, Wei, Wolf, Alexander, Feng, Tianshu, Ho, Chia-hua, Sekirnik, Rok, Zayer, Adam, Granatino, Nicolas, Cockman, Matthew E., Loenarz, Christoph, Loik, Nikita D., Hardy, Adam P., Claridge, Timothy D.W., Hamed, Refaat B., Chowdhury, Rasheduzzaman, Gong, Lingzhi, Robinson, Carol V., Trudgian, David C., Jiang, Miao, Mackeen, Mukram M., Mccullagh, James S., Gordiyenko, Yuliya, Thalhammer, Armin, Yamamoto, Atsushi, Yang, Ming, Liu-Yi, Phebee, Zhang, Zhihong, Schmidt-Zachmann, Marion, Kessler, Benedikt M., Ratcliffe, Peter J., Preston, Gail M., Coleman, Mathew L., Schofield, Christopher J.
Veröffentlicht in Nat Chem Biol (2012)