Novel Insights into FH-associated Disease are KEAPing the Lid on Oncogenic HIF Signalling

Tekijä Adam, Julie, Ratcliffe, Peter J., Pollard, Patrick J.
Julkaistu 2011

Cultural interventions through children's literature and arts-based practices in times of disaster: A case study of reading mediators' response to the Mexican earthquakes (Septembe...

Tekijä Hirsu, Lavinia, Arizpe, Evelyn, McAdam, Julie E.
Julkaisussa Int J Disaster Risk Reduct (2020)

The emerging role of fumarate as an oncometabolite

Tekijä Yang, Ming, Soga, Tomoyoshi, Pollard, Patrick J., Adam, Julie
Julkaistu 2012

Inosine pranobex enhances human NK cell cytotoxicity by inducing metabolic activation and NKG2D ligand expression

Tekijä McCarthy, Michael T., Lin, Da, Soga, Tomoyoshi, Adam, Julie, O'Callaghan, Christopher A.
Julkaisussa Eur J Immunol (2019)

The Succinated Proteome of FH-Mutant Tumours

Tekijä Yang, Ming, Ternette, Nicola, Su, Huizhong, Dabiri, Raliat, Kessler, Benedikt M., Adam, Julie, Teh, Bin Tean, Pollard, Patrick J.
Julkaistu 2014

Purine nucleotide metabolism regulates expression of the human immune ligand MICA

Tekijä McCarthy, Michael T., Moncayo, Gerard, Hiron, Thomas K., Jakobsen, Niels A., Valli, Alessandro, Soga, Tomoyoshi, Adam, Julie, O'Callaghan, Christopher A.
Julkaisussa J Biol Chem (2018)

Cells Lacking the Fumarase Tumor Suppressor Are Protected from Apoptosis through a Hypoxia-Inducible Factor-Independent, AMPK-Dependent Mechanism

Tekijä Bardella, Chiara, Olivero, Martina, Lorenzato, Annalisa, Geuna, Massimo, Adam, Julie, O'Flaherty, Linda, Rustin, Pierre, Tomlinson, Ian, Pollard, Patrick J., Di Renzo, Maria Flavia
Julkaistu 2012

Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes

Tekijä Manuel, Allison M., Walla, Michael D., Faccenda, Adam, Martin, Stephanie L., Tanis, Ross M., Piroli, Gerardo G., Adam, Julie, Kantor, Boris, Mutus, Bulent, Townsend, Danyelle M., Frizzell, Norma
Julkaisussa Antioxid Redox Signal (2017)

Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production

Tekijä Knudsen, Jakob G., Hamilton, Alexander, Ramracheya, Reshma, Tarasov, Andrei I., Brereton, Melissa, Haythorne, Elizabeth, Chibalina, Margarita V., Spégel, Peter, Mulder, Hindrik, Zhang, Quan, Ashcroft, Frances M., Adam, Julie, Rorsman, Patrik
Julkaisussa Cell Metab (2019)

Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)

Tekijä Thalhammer, Armin, Bencokova, Zuzana, Poole, Rachel, Loenarz, Christoph, Adam, Julie, O'Flaherty, Linda, Schödel, Johannes, Mole, David, Giaslakiotis, Konstantinos, Schofield, Christopher J., Hammond, Ester M., Ratcliffe, Peter J., Pollard, Patrick J.
Julkaistu 2011

PHD2 inactivation in Type I cells drives HIF‐2α‐dependent multilineage hyperplasia and the formation of paraganglioma‐like carotid bodies

Tekijä Fielding, James W., Hodson, Emma J., Cheng, Xiaotong, Ferguson, David J. P., Eckardt, Luise, Adam, Julie, Lip, Philomena, Maton‐Howarth, Matthew, Ratnayaka, Indrika, Pugh, Christopher W., Buckler, Keith J., Ratcliffe, Peter J., Bishop, Tammie
Julkaisussa J Physiol (2018)

Increased expression of the diabetes gene SOX4 reduces insulin secretion by impaired fusion pore expansion

Tekijä Collins, Stephan C., Do, Hyun Woong, Hastoy, Benoit, Hugill, Alison, Adam, Julie, Chibalina, Margarita V., Galvanovskis, Juris, Godazgar, Mahdieh, Lee, Sheena, Goldsworthy, Michelle, Salehi, Albert, Tarasov, Andrei I., Rosengren, Anders H., Cox, Roger, Rorsman, Patrik
Julkaisussa Diabetes (2016)

Inhibition of Mitochondrial Aconitase by Succination in Fumarate Hydratase Deficiency

Tekijä Ternette, Nicola, Yang, Ming, Laroyia, Mahima, Kitagawa, Mitsuhiro, O’Flaherty, Linda, Wolhulter, Kathryn, Igarashi, Kaori, Saito, Kaori, Kato, Keiko, Fischer, Roman, Berquand, Alexandre, Kessler, Benedikt M., Lappin, Terry, Frizzell, Norma, Soga, Tomoyoshi, Adam, Julie, Pollard, Patrick J.
Julkaistu 2013

Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism

Tekijä O'Flaherty, Linda, Adam, Julie, Heather, Lisa C., Zhdanov, Alexander V., Chung, Yuen-Li, Miranda, Melroy X., Croft, Joanne, Olpin, Simon, Clarke, Kieran, Pugh, Christopher W., Griffiths, John, Papkovsky, Dmitri, Ashrafian, Houman, Ratcliffe, Peter J., Pollard, Patrick J.
Julkaistu 2010

Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance

Tekijä Nijhuis, Anke, Thompson, Hannah, Adam, Julie, Parker, Alexandra, Gammon, Luke, Lewis, Amy, Bundy, Jacob G., Soga, Tomoyoshi, Jalaly, Aisha, Propper, David, Jeffery, Rosemary, Suraweera, Nirosha, McDonald, Sarah, Thaha, Mohamed A., Feakins, Roger, Lowe, Robert, Bishop, Cleo L., Silver, Andrew
Julkaisussa Hum Mol Genet (2017)

OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation

Tekijä Singleton, Rachelle S., Liu-Yi, Phebee, Formenti, Fabio, Ge, Wei, Sekirnik, Rok, Fischer, Roman, Adam, Julie, Pollard, Patrick J., Wolf, Alexander, Thalhammer, Armin, Loenarz, Christoph, Flashman, Emily, Yamamoto, Atsushi, Coleman, Mathew L., Kessler, Benedikt M., Wappner, Pablo, Schofield, Christopher J., Ratcliffe, Peter J., Cockman, Matthew E.
Julkaistu 2014

Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling

Tekijä Adam, Julie, Hatipoglu, Emine, O'Flaherty, Linda, Ternette, Nicola, Sahgal, Natasha, Lockstone, Helen, Baban, Dilair, Nye, Emma, Stamp, Gordon W., Wolhuter, Kathryn, Stevens, Marcus, Fischer, Roman, Carmeliet, Peter, Maxwell, Patrick H., Pugh, Chris W., Frizzell, Norma, Soga, Tomoyoshi, Kessler, Benedikt M., El-Bahrawy, Mona, Ratcliffe, Peter J., Pollard, Patrick J.
Julkaistu 2011

A Role for Cytosolic Fumarate Hydratase in Urea Cycle Metabolism and Renal Neoplasia

Tekijä Adam, Julie, Yang, Ming, Bauerschmidt, Christina, Kitagawa, Mitsuhiro, O’Flaherty, Linda, Maheswaran, Pratheesh, Özkan, Gizem, Sahgal, Natasha, Baban, Dilair, Kato, Keiko, Saito, Kaori, Iino, Keiko, Igarashi, Kaori, Stratford, Michael, Pugh, Christopher, Tennant, Daniel A., Ludwig, Christian, Davies, Benjamin, Ratcliffe, Peter J., El-Bahrawy, Mona, Ashrafian, Houman, Soga, Tomoyoshi, Pollard, Patrick J.
Julkaistu 2013

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion

Tekijä Vergari, Elisa, Knudsen, Jakob G., Ramracheya, Reshma, Salehi, Albert, Zhang, Quan, Adam, Julie, Asterholm, Ingrid Wernstedt, Benrick, Anna, Briant, Linford J. B., Chibalina, Margarita V., Gribble, Fiona M., Hamilton, Alexander, Hastoy, Benoit, Reimann, Frank, Rorsman, Nils J. G., Spiliotis, Ioannis I., Tarasov, Andrei, Wu, Yanling, Ashcroft, Frances M., Rorsman, Patrik
Julkaisussa Nat Commun (2019)

Somatostatin secretion by Na(+)-dependent Ca(2+)-induced Ca(2+) release in pancreatic delta-cells

Tekijä Vergari, Elisa, Denwood, Geoffrey, Salehi, Albert, Zhang, Quan, Adam, Julie, Alrifaiy, Ahmed, Wernstedt Asterholm, Ingrid, Benrick, Anna, Chibalina, Margarita V., Eliasson, Lena, Guida, Claudia, Hill, Thomas G., Hamilton, Alexander, Ramracheya, Reshma, Reimann, Frank, Rorsman, Nils J. G., Spilliotis, Ioannis, Tarasov, Andrei I., Walker, Jonathan N., Rorsman, Patrik, Briant, Linford J. B.
Julkaisussa Nat Metab (2020)