HIF hydroxylase pathways in cardiovascular physiology and medicine

Por Bishop, Tammie, Ratcliffe, Peter J.
Publicado no Circ Res (2015)

Signaling hypoxia by hypoxia-inducible factor protein hydroxylases: a historical overview and future perspectives

Por Bishop, Tammie, Ratcliffe, Peter J
Publicado no Hypoxia (Auckl) (2014)

Chapter 21: Hyperplasia of Pulmonary Neuroepithelial Bodies (NEB) in Lungs of Prolyl Hydroxylase –1(PHD-1) Deficient Mice

Por Pan, Jie, Yeger, Herman, Ratcliffe, Peter, Bishop, Tammie, Cutz, Ernest
Publicado no Adv Exp Med Biol (2012)

Hyperplasia and hypertrophy of pulmonary neuroepithelial bodies, presumed airway hypoxia sensors, in hypoxia-inducible factor prolyl hydroxylase-deficient mice

Por Pan, Jie, Bishop, Tammie, Ratcliffe, Peter J, Yeger, Herman, Cutz, Ernest
Publicado no Hypoxia (Auckl) (2016)

Hypoxia‐inducible factor 1‐alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl‐4‐hydroxylase 2

Por Hulley, Philippa A, Bishop, Tammie, Vernet, Aude, Schneider, Jurgen E, Edwards, James R, Athanasou, Nick A, Knowles, Helen J
Publicado no J Pathol (2017)

Roles of individual prolyl-4-hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice

Por Chen, Ruo-Li, Nagel, Simon, Papadakis, Michalis, Bishop, Tammie, Pollard, Patrick, Ratcliffe, Peter J, Pugh, Christopher W, Buchan, Alastair M
Publicado em 2012

Genetic Analysis of Pathways Regulated by the von Hippel-Lindau Tumor Suppressor in Caenorhabditis elegans

Por Bishop, Tammie, Lau, Kah Weng, Epstein, Andrew C. R, Kim, Stuart K, Jiang, Min, O'Rourke, Delia, Pugh, Christopher W, Gleadle, Jonathan M, Taylor, Martin S, Hodgkin, Jonathan, Ratcliffe, Peter J
Publicado em 2004

Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF‐2 pathway

Por Hodson, Emma J., Nicholls, Lynn G., Turner, Philip J., Llyr, Ronan, Fielding, James W., Douglas, Gillian, Ratnayaka, Indrika, Robbins, Peter A., Pugh, Christopher W., Buckler, Keith J., Ratcliffe, Peter J., Bishop, Tammie
Publicado no J Physiol (2015)

PHD2 inactivation in Type I cells drives HIF‐2α‐dependent multilineage hyperplasia and the formation of paraganglioma‐like carotid bodies

Por Fielding, James W., Hodson, Emma J., Cheng, Xiaotong, Ferguson, David J. P., Eckardt, Luise, Adam, Julie, Lip, Philomena, Maton‐Howarth, Matthew, Ratnayaka, Indrika, Pugh, Christopher W., Buckler, Keith J., Ratcliffe, Peter J., Bishop, Tammie
Publicado no J Physiol (2018)

Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2

Por Bishop, Tammie, Talbot, Nick P, Turner, Philip J, Nicholls, Lynn G, Pascual, Alberto, Hodson, Emma J, Douglas, Gillian, Fielding, James W, Smith, Thomas G, Demetriades, Marina, Schofield, Christopher J, Robbins, Peter A, Pugh, Christopher W, Buckler, Keith J, Ratcliffe, Peter J
Publicado em 2013

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

Por Chan, Mun Chiang, Atasoylu, Onur, Hodson, Emma, Tumber, Anthony, Leung, Ivanhoe K. H., Chowdhury, Rasheduzzaman, Gómez-Pérez, Verónica, Demetriades, Marina, Rydzik, Anna M., Holt-Martyn, James, Tian, Ya-Min, Bishop, Tammie, Claridge, Timothy D. W., Kawamura, Akane, Pugh, Christopher W., Ratcliffe, Peter J., Schofield, Christopher J.
Publicado no PLoS One (2015)

Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control

Por Cheng, Xiaotong, Prange-Barczynska, Maria, Fielding, James W., Zhang, Minghao, Burrell, Alana L., Lima, Joanna D.C.C., Eckardt, Luise, Argles, Isobel L.A., Pugh, Christopher W., Buckler, Keith J., Robbins, Peter A., Hodson, Emma J., Bruick, Richard K., Collinson, Lucy M., Rastinejad, Fraydoon, Bishop, Tammie, Ratcliffe, Peter J.
Publicado no J Clin Invest (2020)

Silent hypoxaemia in COVID-19 patients

Por Simonson, Tatum S., Baker, Tracy L., Banzett, Robert B., Bishop, Tammie, Dempsey, Jerome A., Feldman, Jack L., Guyenet, Patrice G., Hodson, Emma J., Mitchell, Gordon S., Moya, Esteban A., Nokes, Brandon T., Orr, Jeremy E., Owens, Robert L., Poulin, Marc, Rawling, Jean M., Schmickl, Christopher N., Watters, Jyoti J., Younes, Magdy, Malhotra, Atul
Publicado no J Physiol (2021)

Systemic silencing of Phd2 causes reversible immune regulatory dysfunction

Por Yamamoto, Atsushi, Hester, Joanna, Macklin, Philip S., Kawai, Kento, Uchiyama, Masateru, Biggs, Daniel, Bishop, Tammie, Bull, Katherine, Cheng, Xiaotong, Cawthorne, Eleanor, Coleman, Mathew L., Crockford, Tanya L., Davies, Ben, Dow, Lukas E., Goldin, Rob, Kranc, Kamil, Kudo, Hiromi, Lawson, Hannah, McAuliffe, James, Milward, Kate, Scudamore, Cheryl L., Soilleux, Elizabeth, Issa, Fadi, Ratcliffe, Peter J., Pugh, Chris W.
Publicado no J Clin Invest (2019)

Abnormal Sympathoadrenal Development and Systemic Hypotension in PHD3(−/−) Mice

Por Bishop, Tammie, Gallagher, Denis, Pascual, Alberto, Lygate, Craig A., de Bono, Joseph P., Nicholls, Lynn G., Ortega-Saenz, Patricia, Oster, Henrik, Wijeyekoon, Bhathiya, Sutherland, Andrew I., Grosfeld, Alexandra, Aragones, Julian, Schneider, Martin, van Geyte, Katie, Teixeira, Dania, Diez-Juan, Antonio, Lopez-Barneo, Jose, Channon, Keith M., Maxwell, Patrick H., Pugh, Christopher W., Davies, Alun M., Carmeliet, Peter, Ratcliffe, Peter J.
Publicado em 2008

Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells

Por Wing, Peter A.C., Keeley, Thomas P., Zhuang, Xiaodong, Lee, Jeffrey Y., Prange-Barczynska, Maria, Tsukuda, Senko, Morgan, Sophie B., Harding, Adam C., Argles, Isobel L.A., Kurlekar, Samvid, Noerenberg, Marko, Thompson, Craig P., Huang, Kuan-Ying A., Balfe, Peter, Watashi, Koichi, Castello, Alfredo, Hinks, Timothy S.C., James, William, Ratcliffe, Peter J., Davis, Ilan, Hodson, Emma J., Bishop, Tammie, McKeating, Jane A.
Publicado no Cell Rep (2021)