B cells require DOCK8 to elicit and integrate T cell help when antigen is limiting

Tekijä Deobagkar-Lele, Mukta, Crawford, Greg, Crockford, Tanya L., Back, Jennifer, Hodgson, Rose, Bhandari, Aneesha, Bull, Katherine R, Cornall, Richard J.
Julkaisussa Sci Immunol (2024)

An ontogenetic switch drives the positive and negative selection of B cells

Tekijä Xu, Xijin, Deobagkar-Lele, Mukta, Bull, Katherine R., Crockford, Tanya L., Mead, Adam J., Cribbs, Adam P., Sims, David, Anzilotti, Consuelo, Cornall, Richard J.
Julkaisussa Proc Natl Acad Sci U S A (2020)

Impaired lymphocyte development and antibody class switching and increased malignancy in a murine model of DNA ligase IV syndrome

Tekijä Nijnik, Anastasia, Dawson, Sara, Crockford, Tanya L., Woodbine, Lisa, Visetnoi, Supawan, Bennett, Sophia, Jones, Margaret, Turner, Gareth D., Jeggo, Penelope A., Goodnow, Christopher C., Cornall, Richard J.
Julkaistu 2009

Next-generation sequencing to dissect hereditary nephrotic syndrome in mice identifies a hypomorphic mutation in Lamb2 and models Pierson’s syndrome

Tekijä Bull, Katherine R, Mason, Thomas, Rimmer, Andrew J, Crockford, Tanya L, Silver, Karlee L, Bouriez-Jones, Tiphaine, Hough, Tertius A, Chaudhry, Shirine, Roberts, Ian SD, Goodnow, Christopher C, Cornall, Richard J
Julkaisussa J Pathol (2013)

DOCK8 is essential for T-cell survival and the maintenance of CD8(+) T-cell memory

Tekijä Lambe, Teresa, Crawford, Greg, Johnson, Andy L., Crockford, Tanya L., Bouriez-Jones, Tiphaine, Smyth, Aisling M., Pham, Trung H.M., Zhang, Qian, Freeman, Alexandra F., Cyster, Jason G., Su, Helen C., Cornall, Richard J.
Julkaistu 2011

Themis is a member of a new metazoan gene family and is required for completion of thymocyte positive selection

Tekijä Johnson, Andy L., Aravind, L., Shulzhenko, Natalia, Morgun, Andriy, Choi, See-Young, Crockford, Tanya L., Lambe, Teresa, Domaschenz, Heather, Kucharska, Edyta, Zheng, Lixin, Vinuesa, Carola C., Lenardo, Michael J., Goodnow, Christopher C., Cornall, Richard J., Schwartz, Ronald H.
Julkaistu 2009

Identification of a Steap3 endosomal targeting motif essential for normal iron metabolism

Tekijä Lambe, Teresa, Simpson, Robert J., Dawson, Sara, Bouriez-Jones, Tiphaine, Crockford, Tanya L., Lepherd, Michelle, Latunde-Dada, Gladys O., Robinson, Hannah, Raja, Kishor B., Campagna, Dean R., Villarreal, Guadalupe, Ellory, J. Clive, Goodnow, Christopher C., Fleming, Mark D., McKie, Andrew T., Cornall, Richard J.
Julkaistu 2009

Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity

Tekijä Siggs, Owen M., Stockenhuber, Alexander, Deobagkar-Lele, Mukta, Bull, Katherine R., Crockford, Tanya L., Kingston, Bethany L., Crawford, Greg, Anzilotti, Consuelo, Steeples, Violetta, Ghaffari, Sahar, Czibik, Gabor, Bellahcene, Mohamed, Watkins, Hugh, Ashrafian, Houman, Davies, Benjamin, Woods, Angela, Carling, David, Yavari, Arash, Beutler, Bruce, Cornall, Richard J.
Julkaisussa Proc Natl Acad Sci U S A (2016)

Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis

Tekijä Heazlewood, Chad K, Cook, Matthew C, Eri, Rajaraman, Price, Gareth R, Tauro, Sharyn B, Taupin, Douglas, Thornton, David J, Png, Chin Wen, Crockford, Tanya L, Cornall, Richard J, Adams, Rachel, Kato, Masato, Nelms, Keats A, Hong, Nancy A, Florin, Timothy H. J, Goodnow, Christopher C, McGuckin, Michael A
Julkaistu 2008

Unlocking the Bottleneck in Forward Genetics Using Whole-Genome Sequencing and Identity by Descent to Isolate Causative Mutations

Tekijä Bull, Katherine R., Rimmer, Andrew J., Siggs, Owen M., Miosge, Lisa A., Roots, Carla M., Enders, Anselm, Bertram, Edward M., Crockford, Tanya L., Whittle, Belinda, Potter, Paul K., Simon, Michelle M., Mallon, Ann-Marie, Brown, Steve D. M., Beutler, Bruce, Goodnow, Christopher C., Lunter, Gerton, Cornall, Richard J.
Julkaistu 2013

DOCK8 is critical for the survival and function of NKT cells

Tekijä Crawford, Greg, Enders, Anselm, Gileadi, Uzi, Stankovic, Sanda, Zhang, Qian, Lambe, Teresa, Crockford, Tanya L., Lockstone, Helen E., Freeman, Alexandra, Arkwright, Peter D., Smart, Joanne M., Ma, Cindy S., Tangye, Stuart G., Goodnow, Christopher C., Cerundolo, Vincenzo, Godfrey, Dale I., Su, Helen C., Randall, Katrina L., Cornall, Richard J.
Julkaistu 2013

Systemic silencing of Phd2 causes reversible immune regulatory dysfunction

Tekijä Yamamoto, Atsushi, Hester, Joanna, Macklin, Philip S., Kawai, Kento, Uchiyama, Masateru, Biggs, Daniel, Bishop, Tammie, Bull, Katherine, Cheng, Xiaotong, Cawthorne, Eleanor, Coleman, Mathew L., Crockford, Tanya L., Davies, Ben, Dow, Lukas E., Goldin, Rob, Kranc, Kamil, Kudo, Hiromi, Lawson, Hannah, McAuliffe, James, Milward, Kate, Scudamore, Cheryl L., Soilleux, Elizabeth, Issa, Fadi, Ratcliffe, Peter J., Pugh, Chris W.
Julkaisussa J Clin Invest (2019)

DOCK8 mutations cripple B cell immune synapse, germinal centers and long-lived antibody production

Tekijä Randall, Katrina L., Lambe, Teresa, Johnson, Andy L., Treanor, Bebhinn, Kucharska, Edyta, Domaschenz, Heather, Whittle, Belinda, Tze, Lina E., Enders, Anselm, Crockford, Tanya L., Bouriez-Jones, Tiphaine, Alston, Duncan, Cyster, Jason G., Lenardo, Michael J., Mackay, Fabienne, Deenick, Elissa K., Tangye, Stuart G., Chan, Tyani D., Camidge, Tahra, Brink, Robert, Vinuesa, Carola G., Batista, Facundo D., Cornall, Richard J., Goodnow, Christopher C.
Julkaistu 2009

An essential role for the Zn(2+) transporter ZIP7 in B cell development

Tekijä Anzilotti, Consuelo, Swan, David J., Boisson, Bertrand, Deobagkar-Lele, Mukta, Oliveira, Cathy, Chabosseau, Pauline, Engelhardt, Karin R, Xu, Xijin, Chen, Rui, Alvarez, Luis, Berlinguer-Palmini, Rolando, Bull, Katherine R., Cawthorne, Eleanor, Cribbs, Adam P., Crockford, Tanya L., Dang, Tarana Singh, Fearn, Amy, Fenech, Emma J., de Jong, Sarah J., Lagerholm, B. Christoffer, Ma, Cindy S., Sims, David, van den Berg, Bert, Xu, Yaobo, Cant, Andrew J., Kleiner, Gary, Leahy, T. Ronan, de la Morena, M. Teresa, Puck, Jennifer M., Shapiro, Ralph S., van der Burg, Mirjam, Chapman, J. Ross, Christianson, John C., Davies, Ben, McGrath, John A., Przyborski, Stefan, Koref, Mauro Santibanez, Tangye, Stuart G., Werner, Andreas, Rutter, Guy A., Padilla-Parra, Sergi, Casanova, Jean-Laurent, Cornall, Richard J., Conley, Mary Ellen, Hambleton, Sophie
Julkaisussa Nat Immunol (2019)

High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation

Tekijä Abeler-Dörner, Lucie, Laing, Adam G., Lorenc, Anna, Ushakov, Dmitry S., Clare, Simon, Speak, Anneliese O., Duque-Correa, Maria A., White, Jacqueline K., Ramirez-Solis, Ramiro, Saran, Namita, Bull, Katherine R., Morón, Belén, Iwasaki, Jua, Barton, Philippa R., Caetano, Susana, Hng, Keng I., Cambridge, Emma, Forman, Simon, Crockford, Tanya L., Griffiths, Mark, Kane, Leanne, Harcourt, Katherine, Brandt, Cordelia, Notley, George, Babalola, Kolawole O., Warren, Jonathan, Mason, Jeremy C., Meeniga, Amrutha, Karp, Natasha A., Melvin, David, Cawthorne, Eleanor, Weinrick, Brian, Rahim, Albina, Drissler, Sibyl, Meskas, Justin, Yue, Alice, Lux, Markus, Song-Zhao, George X., Chan, Anna, Reviriego, Carmen Ballesteros, Abeler, Johannes, Wilson, Heather, Przemska-Kosicka, Agnieszka, Edmans, Matthew, Strevens, Natasha, Pasztorek, Markus, Meehan, Terrence F., Powrie, Fiona, Brinkman, Ryan, Dougan, Gordon, Jacobs, William, Lloyd, Clare M., Cornall, Richard J., Maloy, Kevin J., Grencis, Richard K., Griffiths, Gillian M., Adams, David J., Hayday, Adrian C.
Julkaisussa Nat Immunol (2020)