Analysis of an Ethylnitrosourea-generated Mouse Mutation Defines a Cell Intrinsic Role of Nuclear Factor κB2 in Regulating Circulating B Cell Numbers

Tekijä Miosge, Lisa A., Blasioli, Julie, Blery, Mathieu, Goodnow, Christopher C.
Julkaistu 2002

Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-κB in B cell clonal anergy

Tekijä Bléry, Mathieu, Tze, Lina, Miosge, Lisa A., Jun, Jesse E., Goodnow, Christopher C.
Julkaistu 2006

Lack of PTPN22 increases LFA-1-dependent adhesion of Murine Regulatory T Cells improving their regulatory Function

Tekijä Brownlie, Rebecca J, Miosge, Lisa A, Vassilakos, Demetrios, Svensson, Lena M, Cope, Andrew, Zamoyska, Rose
Julkaisussa Sci Signal (2012)

Quantitative reduction of the T cell receptor adapter protein SLP-76 unbalances immunity and immune regulation

Tekijä Siggs, Owen M., Miosge, Lisa A., Daley, Stephen R., Asquith, Kelly, Foster, Paul S., Liston, Adrian, Goodnow, Christopher C.
Julkaisussa J Immunol (2015)

Opposing functions of Zap70 for immunity and tolerance titrate differentially in response to inherited single nucleotide substitutions

Tekijä Siggs, Owen M, Miosge, Lisa A, Yates, Adèle L, Kucharska, Edyta M, Sheahan, Daniel, Brdicka, Tomas, Weiss, Arthur, Liston, Adrian, Goodnow, Christopher C
Julkaistu 2007

Delayed control of herpes simplex virus infection and impaired CD4(+) T cell migration to the skin in mouse models of DOCK8 deficiency

Tekijä Flesch, Inge EA, Randall, Katrina L, Hollett, Natasha A, Law, HseiDi, Miosge, Lisa A, Sontani, Yovina, Goodnow, Christopher C, Tscharke, David C
Julkaisussa Immunol Cell Biol (2015)

A Novel Mutation in Nucleoporin 35 Causes Murine Degenerative Colonic Smooth Muscle Myopathy

Tekijä Parish, Ian A., Stamp, Lincon A., Lorenzo, Ayla May D., Fowler, Suzanne M., Sontani, Yovina, Miosge, Lisa A., Howard, Debbie R., Goodnow, Christopher C., Young, Heather M., Furness, John B.
Julkaisussa Am J Pathol (2016)

Systems-guided forward genetic screen reveals a critical role of the replication stress response protein ETAA1 in T cell clonal expansion

Tekijä Miosge, Lisa A., Sontani, Yovina, Chuah, Aaron, Horikawa, Keisuke, Russell, Tiffany A., Mei, Yan, Wagle, Mayura V., Howard, Debbie R., Enders, Anselm, Tscharke, David C., Goodnow, Christopher C., Parish, Ian A.
Julkaisussa Proc Natl Acad Sci U S A (2017)

Zinc-finger protein ZFP318 is essential for expression of IgD, the alternatively spliced Igh product made by mature B lymphocytes

Tekijä Enders, Anselm, Short, Alanna, Miosge, Lisa A., Bergmann, Hannes, Sontani, Yovina, Bertram, Edward M., Whittle, Belinda, Balakishnan, Bhavani, Yoshida, Kaoru, Sjollema, Geoff, Field, Matthew A., Andrews, T. Daniel, Hagiwara, Hiromi, Goodnow, Christopher C.
Julkaistu 2014

Comparison of predicted and actual consequences of missense mutations

Tekijä Miosge, Lisa A., Field, Matthew A., Sontani, Yovina, Cho, Vicky, Johnson, Simon, Palkova, Anna, Balakishnan, Bhavani, Liang, Rong, Zhang, Yafei, Lyon, Stephen, Beutler, Bruce, Whittle, Belinda, Bertram, Edward M., Enders, Anselm, Goodnow, Christopher C., Andrews, T. Daniel
Julkaisussa Proc Natl Acad Sci U S A (2015)

A point mutation in IKAROS ZF1 causes a B cell deficiency in mice

Tekijä Boast, Brigette, Miosge, Lisa A., Kuehn, Hye Sun, Cho, Vicky, Athanasopoulos, Vicki, McNamara, Hayley A., Sontani, Yovina, Mei, Yan, Howard, Debbie, Sutton, Henry J., Omari, Sofia A., Yu, Zhijia, Nasreen, Mariam, Andrews, T. Daniel, Cockburn, Ian A., Goodnow, Christopher C., Rosenzweig, Sergio D., Enders, Anselm
Julkaisussa J Immunol (2021)

Unlocking the Bottleneck in Forward Genetics Using Whole-Genome Sequencing and Identity by Descent to Isolate Causative Mutations

Tekijä Bull, Katherine R., Rimmer, Andrew J., Siggs, Owen M., Miosge, Lisa A., Roots, Carla M., Enders, Anselm, Bertram, Edward M., Crockford, Tanya L., Whittle, Belinda, Potter, Paul K., Simon, Michelle M., Mallon, Ann-Marie, Brown, Steve D. M., Beutler, Bruce, Goodnow, Christopher C., Lunter, Gerton, Cornall, Richard J.
Julkaistu 2013

Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios(+) T cells and autoantibodies

Tekijä Daley, Stephen R, Coakley, Kristen M, Hu, Daniel Y, Randall, Katrina L, Jenne, Craig N, Limnander, Andre, Myers, Darienne R, Polakos, Noelle K, Enders, Anselm, Roots, Carla, Balakishnan, Bhavani, Miosge, Lisa A, Sjollema, Geoff, Bertram, Edward M, Field, Matthew A, Shao, Yunli, Andrews, T Daniel, Whittle, Belinda, Barnes, S Whitney, Walker, John R, Cyster, Jason G, Goodnow, Christopher C, Roose, Jeroen P
Julkaistu 2013

Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility

Tekijä Wirasinha, Rushika C., Davies, Ainsley R., Srivastava, Monika, Sheridan, Julie M., Sng, Xavier Y.X., Delmonte, Ottavia M., Dobbs, Kerry, Loh, Khai L., Miosge, Lisa A., Lee, Cindy Eunhee, Chand, Rochna, Chan, Anna, Yap, Jin Yan, Keller, Michael D., Chen, Karin, Rossjohn, Jamie, La Gruta, Nicole L., Vinuesa, Carola G., Reid, Hugh H., Lionakis, Michail S., Notarangelo, Luigi D., Gray, Daniel H.D., Goodnow, Christopher C., Cook, Matthew C., Daley, Stephen R.
Julkaisussa J Exp Med (2020)

Antigen-driven EGR2 expression is required for exhausted CD8(+) T cell stability and maintenance

Tekijä Wagle, Mayura V., Vervoort, Stephin J., Kelly, Madison J., Van Der Byl, Willem, Peters, Timothy J., Martin, Ben P., Martelotto, Luciano G., Nüssing, Simone, Ramsbottom, Kelly M., Torpy, James R., Knight, Deborah, Reading, Sinead, Thia, Kevin, Miosge, Lisa A., Howard, Debbie R., Gloury, Renee, Gabriel, Sarah S., Utzschneider, Daniel T., Oliaro, Jane, Powell, Jonathan D., Luciani, Fabio, Trapani, Joseph A., Johnstone, Ricky W., Kallies, Axel, Goodnow, Christopher C., Parish, Ian A.
Julkaisussa Nat Commun (2021)

Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus

Tekijä Jiang, Simon H., Athanasopoulos, Vicki, Ellyard, Julia I., Chuah, Aaron, Cappello, Jean, Cook, Amelia, Prabhu, Savit B., Cardenas, Jacob, Gu, Jinghua, Stanley, Maurice, Roco, Jonathan A., Papa, Ilenia, Yabas, Mehmet, Walters, Giles D., Burgio, Gaetan, McKeon, Kathryn, Byers, James M., Burrin, Charlotte, Enders, Anselm, Miosge, Lisa A., Canete, Pablo F., Jelusic, Marija, Tasic, Velibor, Lungu, Adrian C., Alexander, Stephen I., Kitching, Arthur R., Fulcher, David A., Shen, Nan, Arsov, Todor, Gatenby, Paul A., Babon, Jeff J., Mallon, Dominic F., de Lucas Collantes, Carmen, Stone, Eric A., Wu, Philip, Field, Matthew A., Andrews, Thomas D., Cho, Eun, Pascual, Virginia, Cook, Matthew C., Vinuesa, Carola G.
Julkaisussa Nat Commun (2019)